Neuroanatomic correlates of psychopathologic components of major depressive disorder

MS Milak, RV Parsey, J Keilp… - Archives of General …, 2005 - jamanetwork.com
Background The Hamilton Depression Rating Scale (HDRS) is widely used to measure the
severity of depression in mood disorders. Total HDRS score correlates with brain …

Sleep deprivation PET correlations of Hamilton symptom improvement ratings with changes in relative glucose metabolism in patients with depression

JC Wu, JC Gillin, MS Buchsbaum, C Schachat… - Journal of Affective …, 2008 - Elsevier
BACKGROUND: This PET study is a continuing investigation of the effects of antidepressant
medication and one night of total sleep deprivation on cerebral metabolism in depressed …

Cortical abnormalities and association with symptom dimensions across the depressive spectrum

MS Lener, P Kundu, E Wong, KE Dewilde… - Journal of affective …, 2016 - Elsevier
Background Few studies have investigated the relationship between structural brain
abnormalities and dimensions of depressive symptomatology. Methods In the current study …

Brain metabolic changes associated with symptom factor improvement in major depressive disorder

AL Brody, S Saxena, MA Mandelkern, LA Fairbanks… - Biological …, 2001 - Elsevier
Background: Symptoms of major depressive disorder (MDD) have been linked to regional
brain function through imaging studies of symptom provocation in normal control subjects …

Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression

WC Drevets, JL Price, ML Furey - Brain structure and function, 2008 - Springer
The neural networks that putatively modulate aspects of normal emotional behavior have
been implicated in the pathophysiology of mood disorders by converging evidence from …

Brain structural abnormalities in emotional regulation and sensory processing regions associated with anxious depression

W Peng, Z Jia, X Huang, S Lui, W Kuang… - Progress in Neuro …, 2019 - Elsevier
Background Considerable patients with major depressive disorder (MDD) comorbid with
anxious symptoms, referred as anxious depression. The neural structural basis of this MDD …

Where in the brain is depression?

M Pandya, M Altinay, DA Malone, A Anand - Current psychiatry reports, 2012 - Springer
Major depressive disorder is a serious medical illness which is responsible for considerable
morbidity and disability. Despite decades of research, the neural basis for depression is still …

Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression

WC Drevets - Progress in brain research, 2000 - Elsevier
Neuroimaging studies of major depression have identified neurophysiological abnormalities
in multiple areas of the prefrontal cortex (PFC), the amygdala, and related parts of the …

Regional brain metabolic changes in patients with major depression treated with either paroxetine or interpersonal therapy: preliminary findings

AL Brody, S Saxena, P Stoessel… - Archives of general …, 2001 - jamanetwork.com
Background In functional brain imaging studies of major depressive disorder (MDD),
regional abnormalities have been most commonly found in prefrontal cortex, anterior …

[HTML][HTML] Brain structural and functional changes in patients with major depressive disorder: a literature review

L Dai, H Zhou, X Xu, Z Zuo - PeerJ, 2019 - peerj.com
Depression is a mental disorder characterized by low mood and anhedonia that involves
abnormalities in multiple brain regions and networks. Epidemiological studies demonstrated …