Recent studies have indicated that arachidonic acid is primarily metabolized by cytochrome
P-450 (CYP) enzymes in the brain, lung, kidney, and peripheral vasculature to 20 …

Arachidonic acid (AA) is metabolized by cytochrome P450 (CYP)‐dependent pathways to
epoxyeicosatrienoic acids (EET) and 20‐hydroxyeicosatetraenoic acid (20‐HETE) in the …

Considerable evidence has accumulated over the last decade implicating a role of
cytochrome P450 (CYP)-dependent metabolites of arachidonic acid (AA) in the …

Recent studies indicate that arachidonic acid is primarily metabolized by cytochrome P450
enzymes of the 4A and 2C families in the kidney to 20-hydroxyeicosatetraenoic acid (HETE) …

Recent studies from our laboratory have indicated that vascular smooth muscle cells
(VSMC) metabolize arachidonic acid via a P4504A-dependent pathway to 20 …

Abstract Cytochrome P450s (P450) metabolize arachidonic acid (AA) to
hydroxyeicosatetraenoic acids (HETEs) and epoxyeicosatrienoic acids (EETs). Among these …

Role of 20-hydroxyeicosatetraenoic acid and epoxyeicosatrien... : Current Opinion in
Nephrology and Hypertension Role of 20-hydroxyeicosatetraenoic acid and …

Cytochrome P450s metabolize arachidonic acid to hydroxyeicosatetraenoic acids and
epoxyeicosatrienoic acids. These eicosanoids are formed in a tissue and cell-specific …

The metabolism of arachidonic acid (AA) into vasoactive products by cyclooxygenase and
lipoxygenase enzymes has been well described, as has their biological relevance. Recently …

Endothelial and vascular smooth cells generate cytochrome P450 (CYP) arachidonic acid
metabolites that can impact endothelial cell function and vascular homeostasis. The …