COVID-19 and individual genetic susceptibility/receptivity: role of ACE1/ACE2 genes, immunity, inflammation and coagulation. Might the double X-chromosome in …

D Gemmati, B Bramanti, ML Serino… - International journal of …, 2020 - mdpi.com
In December 2019, a novel severe acute respiratory syndrome (SARS) from a new
coronavirus (SARS-CoV-2) was recognized in the city of Wuhan, China. Rapidly, it became …

ACE and ACE2 Gene Variants Are Associated With Severe Outcomes of COVID-19 in Men

LE Martinez-Gomez, B Herrera-Lopez… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
current coronavirus disease 2019 (COVID-19) pandemic, affecting more than 219 countries …

COVID-19 pandemic: is a gender-defined dosage effect responsible for the high mortality rate among males?

NG De Groot, RE Bontrop - 2020 - Springer
Humankind is currently confronting a new type of coronavirus, and it may take considerable
time before the human population and the virus arrive at a mutual equilibrium. The first …

ACE2 polymorphisms as potential players in COVID-19 outcome

AS Khayat, PP de Assumpção, BC Meireles Khayat… - PLoS …, 2020 - journals.plos.org
The clinical condition COVID-19, caused by SARS-CoV-2, was declared a pandemic by the
WHO in March 2020. Currently, there are more than 5 million cases worldwide, and the …

Racial and gender-based differences in COVID-19

J Kopel, A Perisetti, A Roghani, M Aziz… - Frontiers in public …, 2020 - frontiersin.org
The novel coronavirus disease (COVID-19) has become a global health crisis since its first
appearance in Wuhan, China. Current epidemiological studies suggest that COVID-19 …

Genetic susceptibility of COVID-19: a systematic review of current evidence

SA SeyedAlinaghi, M Mehrtak, M MohsseniPour… - European Journal of …, 2021 - Springer
Introduction While COVID-19 pandemic continues to spread worldwide, researchers have
linked patterns of traits to poor disease outcomes. Risk factors for COVID-19 include asthma …

The impact of ACE2 polymorphisms on COVID-19 disease: susceptibility, severity, and therapy

F Chen, Y Zhang, X Li, W Li, X Liu… - Frontiers in Cellular and …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has currently spread worldwide, leading to high morbidity and …

[HTML][HTML] Role of genetic variants and gene expression in the susceptibility and severity of COVID-19

S Choudhary, K Sreenivasulu, P Mitra… - Annals of laboratory …, 2021 - synapse.koreamed.org
Since its first report in December 2019, coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly emerged as a …

Genetic Association of ACE2 rs2285666 Polymorphism With COVID-19 Spatial Distribution in India

A Srivastava, A Bandopadhyay, D Das… - Frontiers in …, 2020 - frontiersin.org
Studies on host-pathogen interaction have identified human ACE2 as a host cell receptor
responsible for mediating infection by coronavirus (COVID-19). Subsequent studies have …

Investigating the ACE2 polymorphisms in COVID‐19 susceptibility: An in silico analysis

N Pouladi, S Abdolahi - Molecular genetics & genomic …, 2021 - Wiley Online Library
Abstract Background Novel coronavirus (SARS‐CoV‐2) became an epidemic disease and
lead to a pneumonia outbreak first in December 2019 in Wuhan, China. The symptoms …