Atopic dermatitis (AD) is a chronic illness that is associated with immune dysregulation. NK
cell function has previously been associated with AD. NK cells directly interact with …

Natural killer cells (NK) have been associated with the pathophysiology of atopic dermatitis
(AD). NK function is regulated by killer cell Ig-like receptor family (KIR) receptors that interact …

Atopic dermatitis (AD) is a common skin disease of complex etiology including affected
humoral and cellular immune responses. The role of NK cells in development of this disease …

Recently we described an association between psoriasis and KIR2DS1, a gene for a
stimulatory natural killer cell receptor, in a Polish population. The association was …

Atopic dermatitis (AD) is a disease of immune dysregulation and skin barrier dysfunction
with a relapsing, remitting course and has been associated with several different genetic risk …

NK cell activity is partially controlled through interactions between killer Ig-like receptors
(KIR) on NK cells and their respective HLA class I ligands. Independent segregation of HLA …

KIR3DL1 is a polymorphic inhibitory receptor that modulates NK cell activity through
interacting with HLA-A and HLA-B alleles that carry the Bw4 epitope. Amino acid …

Killer cell immunoglobulin-like receptors (KIRs) are a family of cell surface inhibitory or
activating receptors expressed on natural killer cells and some subpopulations of T …

KIR and their HLA ligands are encoded by two of the most diverse gene families in the
human genome. The function of KIR on the NK cell is highly dependent on the normal …

Although HLA‐A3 and A11 have been reported to be ligands for KIR3DL2, evidence for any
in vivo relevance of this interaction is still missing. To explore the functional importance of …