[HTML][HTML] SRT1720 ameliorates sodium taurocholate-induced severe acute pancreatitis in rats by suppressing NF-κB signalling

C Shi, C Hou, X Zhu, D Huang, Y Peng, M Tu… - Biomedicine & …, 2018 - Elsevier
Severe acute pancreatitis (SAP) is a medical emergency that is often associated with
multiple organ failure and high mortality. Although an SAP diagnosis requires prompt …

Catalpol ameliorates sodium taurocholate-induced acute pancreatitis in rats via inhibiting activation of nuclear factor kappa B

WQ Xiao, GJ Yin, YT Fan, L Qiu, XF Cang, G Yu… - International Journal of …, 2014 - mdpi.com
Catalpol, an iridoid glucoside extracted from the traditional Chinese herbal medicine,
Rehmannia glutinosa, is reported to exert neuroprotective, anti-inflammatory, anti-tumor and …

Inhibition of glycogen synthase kinase-3β attenuates acute kidney injury in sodium taurocholate‑induced severe acute pancreatitis in rats

K Zhao, C Chen, Q Shi, W Deng… - Molecular …, 2014 - spandidos-publications.com
The aim of the present study was to investigate the efficacy of 4‑benzyl‑2‑methyl‑1, 2, 4‑
thiadiazolidine‑3, 5‑dione (TDZD‑8), the selective inhibitor of glycogen synthase kinase-3β …

Acanthopanax versus 3‐Methyladenine Ameliorates Sodium Taurocholate‐Induced Severe Acute Pancreatitis by Inhibiting the Autophagic Pathway in Rats

X Wang, G Zhou, C Liu, R Wei, S Zhu… - Mediators of …, 2016 - Wiley Online Library
Objectives. To observe the therapeutic effects of Acanthopanax and 3‐methyladenine
against severe acute pancreatitis (SAP). Methods. Sodium taurocholate‐induced SAP rats …

Artesunate ameliorates severe acute pancreatitis (SAP) in rats by inhibiting expression of pro-inflammatory cytokines and Toll-like receptor 4

Y Cen, C Liu, X Li, Z Yan, M Kuang, Y Su, X Pan… - International …, 2016 - Elsevier
Severe acute pancreatitis (SAP) is a severe clinical condition with significant morbidity and
mortality. Multiple organs dysfunction (MOD) is the leading cause of SAP-related death. The …

Isoliquiritigenin protects against pancreatic injury and intestinal dysfunction after severe acute pancreatitis via Nrf2 signaling

M Zhang, YQ Wu, L Xie, J Wu, K Xu, J Xiao… - Frontiers in …, 2018 - frontiersin.org
Severe acute pancreatitis (SAP) is a digestive system disease that is associated with a
range of complications including intestinal dysfunction. In this study, we determined that the …

Rhein Protects Against Severe Acute Pancreatitis In vitro and In vivo by Regulating the JAK2/STAT3 Pathway

X Yang, H Geng, L You, L Yuan, J Meng… - Frontiers in …, 2022 - frontiersin.org
Rhein is widely used in inflammation treatment in China, but its effects on severe acute
pancreatitis (SAP) have not been studied closely. This study investigated rhein's protective …

Anisodamine alleviates lipopolysaccharide-induced pancreatic acinar cell injury through NLRP3 inflammasome and NF-κB signaling pathway

Z Li, C Xu, Y Tao, Y Liang, Q Liang, J Li… - Journal of Receptors …, 2020 - Taylor & Francis
Abstract Purpose: Anisodamine (An) has anti-inflammatory effects, but its role in acute
pancreatitis is still unknown. This study aimed to explore the action mechanism of An …

Myricetin alleviates pancreatic microcirculation and inflammation in rats with severe acute pancreatitis through FOXO1 and NF-κB pathways

K Ren, J Lin, Y Wang, X Ji - Molecular & Cellular Toxicology, 2023 - Springer
Background Myricetin, a flavonoid, has anti-inflammation effects and can improve pancreatic
β cells dysfunction. However, the role of myricetin in severe acute pancreatitis (SAP) and the …

[HTML][HTML] Iguratimod (T-614) attenuates severe acute pancreatitis by inhibiting the NLRP3 inflammasome and NF-κB pathway

C Hou, X Zhu, C Shi, Y Peng, D Huang, Q Li… - Biomedicine & …, 2019 - Elsevier
Severe acute pancreatitis (SAP) is an acute abdominal disease that can develop locally to
the multiple organs. It is characterized by pancreatic tissue self-digestion, and the rapid …