At its re-birth 30 years ago, the neurodevelopment hypothesis of schizophrenia focussed on
aberrant genes and early neural hazards, but then it grew to include ideas concerning …

It has become increasingly clear that the simple neurodevelopmental model fails to explain
many aspects of schizophrenia including the timing of the onset, and the nature of the …

Schizophrenia is a debilitating disease of major public health importance, the incidence of
which shows prominent worldwide variation (up to fivefold) and is about 40% greater in men …

Two major theories of schizophrenia are respectively, the neurodevelopmental hypothesis
and the dopamine hypothesis. Each of these has recently been revised. Firstly, the classical …

The etiology of schizophrenia has been the focus of intensive research for a long time.
Perspectives have changed drastically with the development of new investigative …

Decades of research on schizophrenia have not produced major breakthroughs, but gradual
progress has been made in identifying risk factors and clarifying the nature of the etiologic …

Major advances have been made in our understanding of the epidemiology of
schizophrenia. We now know that the disorder is more common and severe in young men …

While multiple theories have been put forth regarding the origin of schizophrenia, by far the
vast majority of evidence points to the neurodevelopmental model in which developmental …

Schizophrenia is an aetiologically complex disorder arising from the interaction of a range of
factors acting at various stages of life. Schizophrenic individuals inherit genes that cause …

One of the chief epidemiological hallmarks of schizophrenia is its modal age at onset in
early adulthood. Clinical onset is preceded by an adolescent period that is usually …