Bioinformatics and system biology approaches to identify pathophysiological impact of COVID-19 to the progression and severity of neurological diseases

MH Rahman, HK Rana, S Peng, MG Kibria… - Computers in biology …, 2021 - Elsevier
Abstract The Coronavirus Disease 2019 (COVID-19) still tends to propagate and increase
the occurrence of COVID-19 across the globe. The clinical and epidemiological analyses …

Genetic effects of covid 19 on the development of neurodegenerative diseases

NK Podder, PC Shill, HK Rana… - 2021 5th …, 2021 - ieeexplore.ieee.org
The coronavirus disease (COVID-19) caused by SARS-COV-2, a highly infectious pathogen,
genetically similar to SARS-COV is an unprecedented worldwide health crisis. Rapidly …

Brain disease network analysis to elucidate the neurological manifestations of COVID-19

K Prasad, SY AlOmar, SAM Alqahtani, MZ Malik… - Molecular …, 2021 - Springer
Although COVID-19 largely causes respiratory complications, it can also lead to various
extrapulmonary manifestations resulting in higher mortality and these comorbidities are …

Bioinformatics approach reveals the critical role of the NOD-like receptor signaling pathway in COVID-19-associated multiple sclerosis syndrome

D Qiu, D Zhang, Z Yu, Y Jiang, D Zhu - Journal of Neural Transmission, 2022 - Springer
Multiple sclerosis (MS) is a kind of central nervous system (CNS) autoimmune disease,
which mainly damages nerves, the brain, and the spinal cord. Recently, several clinical …

Analysis and identification genetic effect of SARS-CoV-2 infections to Alzheimer's disease patients by integrated bioinformatics

F Wang, J Xu, SJ Xu, JJ Guo, F Wang… - Journal of Alzheimer's …, 2022 - content.iospress.com
Background: COVID-19 pandemic is a global crisis which results in millions of deaths and
causes long-term neurological sequelae, such as Alzheimer's disease (AD). Objective: We …

Neurological complications of COVID-19: underlying mechanisms and management

GA Shehata, KC Lord, MC Grudzinski… - International Journal of …, 2021 - mdpi.com
COVID-19 is a severe respiratory disease caused by the newly identified human coronavirus
(HCoV) Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The virus was …

Immune mediating molecules and pathogenesis of COVID-19-associated neurological disease

HO Singh, A Singh, AA Khan, V Gupta - Microbial Pathogenesis, 2021 - Elsevier
Background Long period of SARS-CoV-2 infection has been associated with psychiatric and
cognitive disorders in adolescents and children. SARS-CoV-2 remains dormant in the CNS …

Transcriptomic studies revealed pathophysiological impact of COVID-19 to predominant health conditions

Z Nain, SK Barman, MM Sheam, SB Syed… - Briefings in …, 2021 - academic.oup.com
Despite the association of prevalent health conditions with coronavirus disease 2019
(COVID-19) severity, the disease-modifying biomolecules and their pathogenetic …

Shared inflammatory pathology of stroke and COVID-19

KE Sánchez, GA Rosenberg - International Journal of Molecular Sciences, 2022 - mdpi.com
Though COVID-19 is primarily characterized by symptoms in the periphery, it can also affect
the central nervous system (CNS). This has been established by the association between …

Emerging COVID-19 neurological manifestations: present outlook and potential neurological challenges in COVID-19 pandemic

S Dewanjee, J Vallamkondu, RS Kalra… - Molecular …, 2021 - Springer
The unremitting coronavirus disease 2019 (COVID-19) pandemic caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) marked a year-long phase …