Comparison of de-escalation of DAPT intensity or duration in East Asian and Western patients with ACS undergoing PCI: a systematic review and meta-analysis

DA Gorog, V Jeyalan, RIL Markides… - Thrombosis and …, 2023 - thieme-connect.com
Background Guideline-recommended dual antiplatelet therapy (DAPT; aspirin plus
prasugrel/ticagrelor) for 12 months in acute coronary syndrome (ACS) patients increases …

De-escalation of antiplatelet therapy after percutaneous coronary intervention among East Asians and non-East Asians: a meta-analysis of randomized controlled …

G Wang, X Wang, G Zhao, X Huang, R Guo… - BMC Cardiovascular …, 2022 - Springer
Background To study the impact of de-escalation antiplatelet therapy retaining P2Y12
inhibition on major bleeding and ischemic outcomes after percutaneous coronary …

Real-world bleeding in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) and prescribed different combinations of …

M Pufulete, J Harris, K Pouwels, BC Reeves… - Open …, 2022 - openheart.bmj.com
Objective To estimate the incidence and HRs for bleeding for different dual antiplatelet
therapies (DAPT) in a real-world population with acute coronary syndrome (ACS) …

Short duration of DAPT versus de-escalation after percutaneous coronary intervention for acute coronary syndromes

C Laudani, A Greco, G Occhipinti, S Ingala… - Cardiovascular …, 2022 - jacc.org
Objectives The aim of this study was to compare short dual antiplatelet therapy (DAPT) and
de-escalation in a network meta-analysis using standard DAPT as common comparator …

The underutilisation of dual antiplatelet therapy in acute coronary syndrome

M Anastasius, JK Lau, K Hyun, M D'Souza… - International Journal of …, 2017 - Elsevier
Background Despite guideline recommendation of dual antiplatelet therapy (DAPT) in
treating ACS, DAPT is underutilized. Our objective was to determine independent predictors …

[HTML][HTML] Shortening dual antiplatelet therapy duration in high-risk patients undergoing percutaneous coronary intervention

A Greco, D Capodanno - JACC: Asia, 2023 - jacc.org
(PCI), a 6-to 12-month course of dual antiplatelet therapy (DAPT) with aspirin and a P2Y12
receptor inhibitor is typically prescribed to mitigate the risk of thrombotic complications at the …

Tailoring oral antiplatelet therapy in acute coronary syndromes: from guidelines to clinical practice

S De Servi, A Landi, S Savonitto… - Journal of …, 2023 - journals.lww.com
The assessment of bleeding and ischemic risk is a crucial step in establishing appropriate
composition and duration of dual antiplatelet therapy (DAPT) in patients with acute coronary …

De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an …

DA Gorog, JL Ferreiro, I Ahrens, J Ako… - Nature Reviews …, 2023 - nature.com
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes
undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y …

Reduced mortality with antiplatelet therapy deescalation after percutaneous coronary intervention in acute coronary syndromes: a meta-analysis

T Palmerini, AG Bruno, M Gasparini… - Circulation …, 2022 - Am Heart Assoc
Background: Antiplatelet therapy deescalation has been suggested as an alternative to
standard treatment with potent dual antiplatelet therapy (DAPT) for 1 year in low bleeding …

Escalation and de-escalation of antiplatelet therapy after acute coronary syndrome or PCI: Available evidence and implications for practice

F Gragnano, A Capolongo, F Terracciano… - Journal of Clinical …, 2022 - mdpi.com
Dual antiplatelet therapy (DAPT) is the gold standard for the antithrombotic management of
patients with an acute coronary syndrome (ACS) or undergoing percutaneous coronary …