Despite the evolutionary loss of tissue regenerative potential, robust skeletal muscle repair
processes are largely retained even in higher vertebrates. In mammals, the skeletal muscle …

The capacity of adult muscle to regenerate in response to injury stimuli represents an
important homeostatic process. Regeneration is a highly coordinated program that partially …

One of the most fascinating questions in regenerative biology is why some animals can
regenerate injured structures while others cannot. Skeletal muscle has a remarkable …

Skeletal muscle is a highly specialized tissue composed of non-dividing, multi-nucleated
muscle fibres that contract to generate force in a controlled and directed manner. Skeletal …

Skeletal muscle is an ideal target for cell therapy. The use of its potent stem cell population
in the form of autologous intramuscular transplantation represents a tantalizing strategy to …

Skeletal muscle has an extraordinary regenerative capacity due to the activity of tissue-
specific muscle stem cells. Consequently, these cells have received the most attention in …

Cells with contractile functions are present in almost all metazoans, and so are the related
processes of muscle homeostasis and regeneration. Regeneration itself is a complex …

Adult skeletal muscle maintains a homeostatic state with modest levels of cellular turnover,
unlike the skin or blood. However, the muscle is highly sensitive to tissue injury, which …

Skeletal muscle, a tissue endowed with remarkable endogenous regeneration potential, is
still under focused experimental investigation mainly due to treatment potential for muscle …

Skeletal muscle is a structurally and functionally remarkable tissue composed of
multinucleated post‐mitotic muscle fibres. These fibres are filled with an exquisite, near …