Resistance and Adaptation to Quinidine in Saccharomyces cerevisiae: Role of QDR1 (YIL120w), Encoding a Plasma Membrane Transporter of the Major Facilitator …

PA Nunes, S Tenreiro, I Sá-Correia - Antimicrobial agents and …, 2001 - Am Soc Microbiol
As predicted based on structural considerations, we show results indicating that the member
of the major facilitator superfamily encoded by Saccharomyces cerevisiae open reading …

Saccharomyces cerevisiae Multidrug Transporter Qdr2p (Yil121wp): Localization and Function as a Quinidine Resistance Determinant

RC Vargas, S Tenreiro, MC Teixeira… - Antimicrobial agents …, 2004 - Am Soc Microbiol
This work reports the functional analysis of Saccharomyces cerevisiae open reading frame
YIL121w, encoding a member of a family of drug: H+ antiporters with 12 predicted …

Role of the yeast multidrug transporter Qdr2 in cation homeostasis and the oxidative stress response

G Ríos, M Cabedo, B Rull, L Yenush… - FEMS yeast …, 2013 - academic.oup.com
We have identified QDR2 in a screening for genes able to confer tolerance to sodium and/or
lithium stress upon overexpression. Qdr2 is a multidrug transporter of the major facilitator …

The yeast multidrug transporter Qdr3 (Ybr043c): localization and role as a determinant of resistance to quinidine, barban, cisplatin, and bleomycin

S Tenreiro, RC Vargas, MC Teixeira, C Magnani… - Biochemical and …, 2005 - Elsevier
Saccharomyces cerevisiae ORF YBR043c, predicted to code for a transporter of the major
facilitator superfamily required for multiple drug resistance, encodes a plasma membrane …

Saccharomyces cerevisiae Multidrug Resistance Transporter Qdr2 Is Implicated in Potassium Uptake, Providing a Physiological Advantage to Quinidine-Stressed …

RC Vargas, R García-Salcedo, S Tenreiro… - Eukaryotic …, 2007 - Am Soc Microbiol
The QDR2 gene of Saccharomyces cerevisiae encodes a putative plasma membrane drug:
H+ antiporter that confers resistance against quinidine, barban, bleomycin, and cisplatin …

AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids …

S Tenreiro, PA Nunes, CA Viegas, MS Neves… - Biochemical and …, 2002 - Elsevier
We report results on the functional analysis of Saccharomyces cerevisiae ORF YNL065w,
predicted to code for a protein belonging to the poorly characterized major facilitator …

Expression of the AZR1 gene (ORF YGR224w), encoding a plasma membrane transporter of the major facilitator superfamily, is required for adaptation to acetic acid and …

S Tenreiro, PC Rosa, CA Viegas, I Sá‐Correia - Yeast, 2000 - Wiley Online Library
In this work, we report results on the functional analysis of Saccharomyces cerevisiae ORF
YGR224w, predicted to code for an integral membrane protein, with 14 potential …

Identification of Saccharomyces cerevisiae Genes Conferring Resistance to Quinoline Ring-Containing Antimalarial Drugs

U Delling, M Raymond, E Schurr - Antimicrobial agents and …, 1998 - Am Soc Microbiol
To identify genes that can confer resistance to antimalarial drugs in yeast, we transformed
the quinidine-sensitive strain CYX247-9A of Saccharomyces cerevisiae with a yeast …

Yeast response and tolerance to polyamine toxicity involving the drug : H+ antiporter Qdr3 and the transcription factors Yap1 and Gcn4

MC Teixeira, TR Cabrito, ZM Hanif… - …, 2011 - microbiologyresearch.org
The yeast QDR3 gene encodes a plasma membrane drug: H+ antiporter of the DHA1 family
that was described as conferring resistance against the drugs quinidine, cisplatin and …

Novel target genes of the yeast regulator Pdr1p: a contribution of the TPO1 gene in resistance to quinidine and other drugs

MA do Valle Matta, JL Jonniaux, E Balzi, A Goffeau… - Gene, 2001 - Elsevier
The yeast transcription factor Pdr1p regulates the expression of a number of genes, several
of which encode ATP-driven transport proteins involved in multiple drug resistance. Among …