[HTML][HTML] Neuroinflammation and neurogenesis in Alzheimer's disease and potential therapeutic approaches

PS Sung, PY Lin, CH Liu, HC Su, KJ Tsai - International journal of …, 2020 - mdpi.com
In adult brain, new neurons are generated throughout adulthood in the subventricular zone
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …

Cellular and molecular influencers of neuroinflammation in Alzheimer's disease: recent concepts & roles

P Ghosh, R Singh, A Ganeshpurkar, AV Pokle… - Neurochemistry …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), an extremely common neurodegenerative disorder of the
older generation, is one of the leading causes of death globally. Besides the conventional …

[HTML][HTML] New insights into neuroinflammation involved in pathogenic mechanism of Alzheimer's disease and its potential for therapeutic intervention

T Li, L Lu, E Pember, X Li, B Zhang, Z Zhu - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common form of dementia, affecting more than 50
million people worldwide with an estimated increase to 139 million people by 2050. The …

[HTML][HTML] Neuroinflammatory signaling in the pathogenesis of Alzheimer's disease

MS Uddin, MT Kabir, M Jalouli… - Current …, 2022 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the
formation of intracellular neurofibrillary tangles (NFTs) and extracellular amyloid plaques …

Role of neuroinflammation in adult neurogenesis and Alzheimer disease: therapeutic approaches

A Fuster-Matanzo, M Llorens-Martín… - Mediators of …, 2013 - Wiley Online Library
Neuroinflammation, a specialized immune response that takes place in the central nervous
system, has been linked to neurodegenerative diseases, and specially, it has been …

Neuroinflammation, immune system and Alzheimer disease: searching for the missing link

F Guerriero, C Sgarlata, M Francis, N Maurizi… - Aging clinical and …, 2017 - Springer
Due to an increasingly aging population, Alzheimer disease (AD) represents a crucial issue
for the healthcare system because of its widespread prevalence and the burden of its care …

[HTML][HTML] Targeting neuroinflammation in Alzheimer's disease: From mechanisms to clinical applications

ZZ Si, CJ Zou, X Mei, XF Li, H Luo, Y Shen… - Neural regeneration …, 2023 - journals.lww.com
Alzheimer's disease is characterized by sustained neuroinflammation leading to memory
loss and cognitive decline. The past decade has witnessed tremendous efforts in …

[HTML][HTML] Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel therapeutic approaches

I Morales, L Guzmán-Martínez… - Frontiers in cellular …, 2014 - frontiersin.org
Alzheimer disease (AD) is the most common cause of dementia in people over 60 years old.
The molecular and cellular alterations that trigger this disease are still diffuse, one of the …

[HTML][HTML] Inflammatory cascade in Alzheimer's disease pathogenesis: A review of experimental findings

J de Oliveira, E Kucharska, ML Garcez, MS Rodrigues… - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Most AD patients
develop the disease in late life, named late onset AD (LOAD). Currently, the most …

[HTML][HTML] Molecular mechanisms of neuroinflammation in aging and Alzheimer's disease progression

FL Andronie-Cioara, AI Ardelean… - International journal of …, 2023 - mdpi.com
Aging is the most prominent risk factor for late-onset Alzheimer's disease. Aging associates
with a chronic inflammatory state both in the periphery and in the central nervous system, the …