[HTML][HTML] Alkyl organophosphate flame retardants (OPFRs) induce lung inflammation and aggravate OVA-simulated asthmatic response via the NF-кB signaling …

Y Meng, X Xu, G Xie, Y Zhang, S Chen, Y Qiu… - Environment …, 2022 - Elsevier
Alkyl organophosphate flame retardants (OPFRs), tri-n-butyl phosphate (TnBP) and tris (2-
butoxyethyl) phosphate (TBOEP), are ubiquitously detected in indoor and outdoor …

Chlorinated organophosphate flame retardants impair the lung function via the IL-6/JAK/STAT signaling pathway

H Zhu, H Zhang, K Lu, S Yang, X Tang… - Environmental …, 2022 - ACS Publications
Toxicological studies have revealed the adverse impacts of organophosphate flame
retardants (OPFRs) on the respiratory system, while there is a lack of epidemiological …

OPFRs and BFRs induced A549 cell apoptosis by caspase-dependent mitochondrial pathway

X Yu, H Yin, H Peng, G Lu, Z Liu, Z Dang - Chemosphere, 2019 - Elsevier
Organophosphate flame retardants (OPFRs) and brominated flame retardants (BFRs) are
frequently detected in indoor environment at high levels, posing health risks to humans …

The respiratory cytotoxicity of typical organophosphorus flame retardants on five different respiratory tract cells: Which are the most sensitive one?

J Chen, G Li, H Yu, H Liu, T An - Environmental Pollution, 2022 - Elsevier
Triphenyl phosphate (TPHP) is a frequently used flame retardant and indoor semi-volatile
pollutant exposing humans with endocrinal disrupting effects. However, its respiratory tract …

[HTML][HTML] Suppression of Fpr2 expression protects against endotoxin-induced acute lung injury by interacting with Nrf2-regulated TAK1 activation

H Liu, Z Lin, Y Ma - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Acute lung injury (ALI) is caused by severe infection, and urgently needs effective treatments
or validated pharmacological targets. Formyl peptide receptor 2 (Fpr2) plays essential roles …

Organophosphate flame retardants induce oxidative stress and Chop/Caspase 3-related apoptosis via Sod1/p53/Map3k6/Fkbp5 in NCI-1975 cells

Y Meng, X Xu, D Niu, Y Xu, Y Qiu, Z Zhu… - Science of the Total …, 2022 - Elsevier
Organophosphate flame retardants (OPFRs) have been ubiquitously detected in dust and air
which could cause damage to human health through inhalation. Currently the understanding …

Triphenyl phosphate‐induced macrophages dysfunction by activation TLR4‐mediated ERK/NF‐κB pathway

Z Lin, W Zhang, X Li, B Du, T Li, H He… - Environmental …, 2023 - Wiley Online Library
Triphenyl phosphate (TPHP) is one of the most widely used organic phosphorus flame
retardants and is ubiquitous in the environment. Studies have been reported that TPHP may …

Mediation of endoplasmic reticulum stress and NF-κB signaling pathway in DINP-exacerbated allergic asthma: A toxicological study with Balb/c mice

F Lei, Y Wu, C Li, B Yan, S Chen, Q Peng… - Journal of Hazardous …, 2023 - Elsevier
Epidemiological evidence indicates a significant relationship between exposure to
diisononyl phthalate and allergic asthma. Despite this, the mechanism underlying this …

[HTML][HTML] Dietary exposure to flame retardant tris (2-butoxyethyl) phosphate altered neurobehavior and neuroinflammatory responses in a mouse model of allergic …

TT Win-Shwe, R Yanagisawa, TT Lwin… - International Journal of …, 2022 - mdpi.com
Tris (2-butoxyethyl) phosphate (TBEP) is an organophosphate flame retardant and used as
a plasticizer in various household products such as plastics, floor polish, varnish, textiles …

[HTML][HTML] Contamination profiles and potential health risks of organophosphate flame retardants in PM2. 5 from Guangzhou and Taiyuan, China

Y Chen, Y Song, YJ Chen, Y Zhang, R Li, Y Wang… - Environment …, 2020 - Elsevier
Organophosphate flame retardants (OPFRs) are emerging contaminants in recent years.
They can be present in the atmospheric fine particle (PM 2.5), leading to potential adverse …