GA Herman, MP O'Brien, E Forleo-Neto… - The Lancet Infectious …, 2022 - thelancet.com
Background There is an unmet need for COVID-19 prevention in patient populations who have not mounted or are not expected to mount an adequate immune response to complete …
MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - Jama, 2022 - jamanetwork.com
Importance Easy-to-administer anti–SARS-CoV-2 treatments may be used to prevent progression from asymptomatic infection to symptomatic disease and to reduce viral …
EK McCreary, JR Bariola, RJ Wadas… - JAMA Network …, 2022 - jamanetwork.com
Importance Monoclonal antibody (mAb) treatment decreases hospitalization and death in high-risk outpatients with mild to moderate COVID-19; however, only intravenous …
C Portal-Celhay, E Forleo-Neto, W Eagan… - JAMA Network …, 2022 - jamanetwork.com
Importance The monoclonal antibody combination of casirivimab and imdevimab reduced viral load, hospitalization, or death when administered as a 1200-mg or greater intravenous …
M Hussein, W Wei, V Mastey, RJ Sanchez, D Wang… - BMJ open, 2022 - bmjopen.bmj.com
Objective To assess the real-world effectiveness of casirivimab and imdevimab (CAS+ IMD) versus no COVID-19 antibody treatment among patients diagnosed with COVID-19 in the …
C Portal-Celhay, E Forleo-Neto, W Eagan, BJ Musser… - medRxiv, 2021 - medrxiv.org
Background The monoclonal antibody combination casirivimab and imdevimab (REGEN- COV®) reduced viral load, hospitalisation, or death when administered 1: 1 as an …
Background Real-world clinical data to support the use of casirivimab–imdevimab for the treatment of outpatients with mild to moderate coronavirus disease-19 (COVID-19) is …
Abstract Casirivimab/imdevimab (Ronapreve™; REGEN-COV™) is a co-packaged combination of two neutralizing immunoglobulin gamma 1 (IgG1) human monoclonal …
O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2022 - thelancet.com
Background Casirivimab and imdevimab are non-competing monoclonal antibodies that bind to two different sites on the receptor binding domain of the SARS-CoV-2 spike …