Copper is an essential metal required for many metalloproteins' function. A fraction of dietary
copper (average 2–5 mg/day) is absorbed by enterocytes in the duodenum and proximal …

Copper is an essential metal that is an important cofactor for many proteins. The average
diet provides substantial amounts of copper, typically 2-5 mg/day; the recommended intake …

This guideline is intended for use by physicians. It describes preferable up-to-date
approaches to the diagnosis and treatment of patients with Wilson disease. As their purpose …

This Clinical Practice Guideline (CPG) has been developed to assist physicians and other
healthcare providers in the diagnosis and management of patients with Wilson's disease …

Current and Emerging Issues in Wilson’s Disease | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …

Nearly a century after Dr. Samuel Alexander Kinnier Wilson composed his doctoral thesis on
the pathologic findings of “lenticular degeneration” in the brain associated with cirrhosis of …

Background and Aims In 1984, Scheinberg and Sternlieb estimated the prevalence of
Wilson's disease to be 1: 30,000 based on the limited available data. This suggested a large …

Wilson's disease is a rare, inherited autosomal recessive disease of copper metabolism, in
which the causative gene, ATP7B, results in absent or reduced function of the ATP7B …

Wilson's disease (WD) is a rare condition caused by copper accumulation primarily in the
liver and secondly in other organs, such as the central nervous system. It is a hereditary …

Three guidelines in Wilson disease (WD) have been issued to date: by the American
Association for the Study of Liver Diseases (AASLD) in 2003 with revision in 2008, by the …