Retinoids are known to induce the differentiation and cell cycle arrest of human myeloid
leukemia cells in vitro. Differential display was used to identify putative early regulatory …

Upstream signaling requirements of retinoic acid (RA)-induced blr1 expression and
downstream signaling consequences of blr1 over-expression in a human myeloid leukemia …

The mechanism of action of retinoic acid (RA) is of broad relevance to cell and
developmental biology, nutrition, and cancer chemotherapy. RA is known to induce …

The product of the blr1 gene is a CXC chemokine receptor (CXCR5) that regulates B
lymphocyte migration and has been implicated in myelomonocytic differentiation. The U937 …

MAPK signaling is required for retinoic acid (RA)-triggered G 0 cell cycle arrest and cell
differentiation, but the mechanism is not well defined. In this study, RA is found to cause …

OBJECTIVE: All-trans-retinoic acid (RA) is a potent inducer of differentiation of acute
promyelocytic leukemia (APL) cells in vitro and in vivo. It also exhibits synergistic effects with …

Retinoids induce granulocytic differentiation and subsequent apoptosis in human myeloid
(HL-60) leukemia cells. Differentiation is induced due to activation of retinoic acid receptors …

Retinoic acid is known to cause the myeloid differentiation and G1/0 cell cycle arrest of HL-
60 cells in a process that requires mitogen-activated protein/extracellular signal regulated …

We have previously shown that forced expression of the transcription factor Scl in WEHI-3B
D+ cells prevents ATRA-induced cell differentiation. We now find that the overexpression of …

Abstract Bryostatin 1 (bryo 1) is known to induce the differentiation and cell cycle arrest of
human lymphoid leukemia cells in vitro. The extracellular signal-regulated kinase (ERK) …