Myrtenol Inhalation Mitigates Asthma-Induced Cognitive Impairments: an Electrophysiological, Behavioral, Histological, and Molecular Study

K Esmaeilpour, E Jafari, F Rostamabadi… - Molecular …, 2023 - Springer
Asthma is an inflammatory disorder with significant health problems. It generally affects the
lungs but can also impact brain performance via several mechanisms. Some investigations …

Myrtenol ameliorates recognition memories' impairment and anxiety-like behaviors induced by asthma by mitigating hippocampal inflammation and oxidative stress in …

MA Bejeshk, AH Aminizadeh, E Jafari… - …, 2023 - karger.com
Introduction: Asthma is related to neurochemical alterations which affect brain functions and
lead to anxiety and cognitive dysfunctions. Myrtenol has sparked considerable interest due …

Allergic asthma-induced cognitive impairment is alleviated by dexamethasone

M Ren, M Feng, Z Long, J Ma, X Peng… - Frontiers in …, 2021 - frontiersin.org
Allergic asthma is a typical chronic inflammatory disease of respiratory tract. Clinical data
shows that patients with allergic asthma have different degrees of cognitive dysfunction. The …

Inhaled budesonide protects against chronic asthma-induced neuroinflammation in mouse brain

MX Xia, X Ding, J Qi, J Gu, G Hu, XL Sun - Journal of neuroimmunology, 2014 - Elsevier
Chronic asthma is one of the most common respiratory diseases, characterized by airway
inflammation. However, little is known whether asthma-induced airway inflammation might …

[HTML][HTML] Glycyrrhiza uralensis flavonoids inhibit brain microglial cell TNF-α secretion, p-IκB expression, and increase brain-derived neurotropic factor (BDNF) secretion

SP Patil, C Liu, J Alban, N Yang, XM Li - Journal of Traditional Chinese …, 2014 - Elsevier
Objective Asthma sufferers exhibit high prevalence of anxiety/depression. Elevated tumor-
necrosis factor-alpha (TNF-α) levels in peripheral system and central nervous system (CNS) …

Icariin protects hippocampal neurons from endoplasmic reticulum stress and NF-κB mediated apoptosis in fetal rat hippocampal neurons and asthma rats

J Liu, L Liu, J Sun, Q Luo, C Yan, H Zhang… - Frontiers in …, 2020 - frontiersin.org
Icariin is a main component of the Chinese medicinal plant Epimedium brevicornu Maxim,
exhibits potent activity against inflammatory diseases. Our previous data demonstrated the …

Anti-inflammatory and anti-remodeling effects of myrtenol in the lungs of asthmatic rats: histopathological and biochemical findings

MA Bejeshk, MS Fekri, H Najafipour… - Allergologia et …, 2019 - Elsevier
Introduction Asthma is a chronic inflammatory disease of the airways. In this study, we
evaluated the anti-inflammatory effects of myrtenol on the inflammatory indices in the …

Effects of inhaled corticosteroids on brain volumetry, depression and anxiety-like behaviors in a rat model of asthma

K Dehdar, MR Raoufy - Respiratory Physiology & Neurobiology, 2023 - Elsevier
Brain functional deficits have been reported in asthma patients which can result in
behavioral disorders like depression and anxiety. These deficits may be associated with …

Allergen induces depression-like behavior in association with altered prefrontal-hippocampal circuit in male rats

K Dehdar, M Salimi, F Tabasi, S Dehghan, A Sumiyoshi… - Neuroscience, 2023 - Elsevier
Allergic asthma is a common chronic inflammatory condition associated with psychiatric
comorbidities. Notably depression, correlated with adverse outcomes in asthmatic patients …

Airway inflammation induces anxiety-like behavior through neuroinflammatory, neurochemical, and neurometabolic changes in an allergic asthma model

GL Antunes, JS Silveira, C Luft, S Greggio… - Metabolic Brain …, 2022 - Springer
Allergic asthma is characterized by chronic airway inflammation and is constantly associated
with anxiety disorder. Recent studies showed bidirectional interaction between the brain and …