Modeling SARS-CoV-2 viral kinetics and association with mortality in hospitalized patients from the French COVID cohort

N Néant, G Lingas, Q Le Hingrat… - Proceedings of the …, 2021 - National Acad Sciences
The characterization of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
viral kinetics in hospitalized patients and its association with mortality is unknown. We …

Kinetics of SARS-CoV-2 infection in the human upper and lower respiratory tracts and their relationship with infectiousness

R Ke, C Zitzmann, RM Ribeiro, AS Perelson - MedRxiv, 2020 - medrxiv.org
SARS-CoV-2 is a human pathogen that causes infection in both the upper respiratory tract
(URT) and the lower respiratory tract (LRT). The viral kinetics of SARS-CoV-2 infection and …

[HTML][HTML] Association of initial viral load in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients with outcome and symptoms

KV Argyropoulos, A Serrano, J Hu, M Black… - The American journal of …, 2020 - Elsevier
The dynamics of viral load (VL) of the severe acute respiratory syndrome coronavirus 2 and
its association with different clinical parameters remain poorly characterized in the US …

[HTML][HTML] Duration of SARS-CoV-2 viremia and its correlation to mortality and inflammatory parameters in patients hospitalized for COVID-19: a cohort study

K Hagman, M Hedenstierna, J Rudling… - … and infectious disease, 2022 - Elsevier
SARS-CoV-2 viremia at admission is associated with high risk for mortality. However,
longitudinal data on viremia duration are limited. Viremic patients hospitalized for COVID-19 …

[HTML][HTML] SARS-CoV-2 viral dynamics in non-human primates

A Gonçalves, P Maisonnasse, F Donati… - PLoS computational …, 2021 - journals.plos.org
Non-human primates infected with SARS-CoV-2 exhibit mild clinical signs. Here we used a
mathematical model to characterize in detail the viral dynamics in 31 cynomolgus macaques …

Modeling the effects of intervention strategies on COVID-19 transmission dynamics

DM Kennedy, GJ Zambrano, Y Wang… - Journal of Clinical Virology, 2020 - Elsevier
Objectives To model the effects of continuous, intermittent, and stepping-down social
distancing (SD) strategies and personal protection measures on COVID-19 transmission …

Timing of antiviral treatment initiation is critical to reduce SARS‐CoV‐2 viral load

A Gonçalves, J Bertrand, R Ke… - CPT …, 2020 - Wiley Online Library
We modeled the viral dynamics of 13 untreated patients infected with severe acute
respiratory syndrome‐coronavirus 2 to infer viral growth parameters and predict the effects …

Clinical characteristics and factors associated with long-term viral excretion in patients with severe acute respiratory syndrome coronavirus 2 infection: a single-center …

D Shi, W Wu, Q Wang, K Xu, J Xie, J Wu… - The Journal of …, 2020 - academic.oup.com
Background Despite the ongoing spread of coronavirus disease 2019 (COVID-19),
knowledge about factors affecting prolonged viral excretion is limited. Methods In this study …

[HTML][HTML] Viral kinetics of SARS-CoV-2 over the preclinical, clinical, and postclinical period

S Jang, JY Rhee, YM Wi, BK Jung - International Journal of Infectious …, 2021 - Elsevier
Background It is necessary to know the viral kinetics and conduct epidemiological
investigations of confirmers to prevent the spread of the new infectious disease COVID-19 to …

Survival in adult inpatients with COVID-19

E Murillo-Zamora, CM Hernandez-Suarez - Public health, 2021 - Elsevier
Background The mortality of the coronavirus disease 2019 (COVID-19) pandemic is high,
and data regarding its prognosis are scarce. We aimed to assess the survival experience …