Post‐translational regulation of muscle growth, muscle aging and sarcopenia

Q Zhong, K Zheng, W Li, K An, Y Liu… - Journal of Cachexia …, 2023 - Wiley Online Library
Abstract Skeletal muscle makes up 30–40% of the total body mass. It is of great significance
in maintaining digestion, inhaling and exhaling, sustaining body posture, exercising …

[HTML][HTML] Skeletal muscle in age-related diseases: From molecular pathogenesis to potential interventions

MS Parvatiyar, R Qaisar - Frontiers in Physiology, 2022 - frontiersin.org
Skeletal muscle is a dynamic organ that responds to various stimuli by altering its size,
strength, and composition. Maintenance of skeletal muscle mass and strength is critical for …

[HTML][HTML] Sarcopenia–Molecular mechanisms and open questions

P Wiedmer, T Jung, JP Castro, LCD Pomatto… - Ageing research …, 2021 - Elsevier
Sarcopenia represents a muscle-wasting syndrome characterized by progressive and
generalized degenerative loss of skeletal muscle mass, quality, and strength occurring …

[HTML][HTML] Skeletal muscle aging: influence of oxidative stress and physical exercise

MJ Gomes, PF Martinez, LU Pagan, RL Damatto… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Skeletal muscle abnormalities are responsible for significant disability in the elderly.
Sarcopenia is the main alteration occurring during senescence and a key public health …

[HTML][HTML] Pathophysiology and mechanisms of primary sarcopenia

H Nishikawa, S Fukunishi, A Asai… - International …, 2021 - spandidos-publications.com
Aging causes skeletal muscle atrophy, and myofiber loss can be a critical component of this
process. In 1989, Rosenberg emphasized the importance of the loss of skeletal muscle …

Skeletal muscle: increasing the size of the locomotor cell

LG Karagounis, JA Hawley - The international journal of biochemistry & cell …, 2010 - Elsevier
Skeletal muscle is the most abundant tissue in the body comprising 40–50% of body mass in
humans and playing a central role in maintaining metabolic health. Skeletal muscle protein …

Sarcopenia of aging and its metabolic impact

H Karakelides, KS Nair - Current topics in developmental biology, 2005 - Elsevier
Sarcopenia contributes significantly to the morbidity, decrease in quality of life, and health
care costs in the elderly. It is characterized by a decrease in muscle mass and strength …

Skeletal muscle protein balance and metabolism in the elderly

CS Fry, BB Rasmussen - Current Aging Science, 2011 - ingentaconnect.com
The loss of lean muscle mass occurring with advancing age is termed sarcopenia. This
condition often leads to a concomitant loss of strength, increased frailty and risk of falls and …

[HTML][HTML] Molecular mechanisms and therapeutic interventions in sarcopenia

SS Park, ES Kwon, KS Kwon - Osteoporosis and sarcopenia, 2017 - Elsevier
Sarcopenia is the degenerative loss of muscle mass and function with aging. Recently
sarcopenia was recognized as a clinical disease by the International Classification of …

Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness

JG Ryall, JD Schertzer, GS Lynch - Biogerontology, 2008 - Springer
Some of the most serious consequences of ageing are its effects on skeletal muscle. The
term 'sarcopenia'describes the slow but progressive loss of muscle mass with advancing …