[HTML][HTML] Sex differences in the genetic and molecular mechanisms of coronary artery disease

TR Sakkers, M Mokry, M Civelek, J Erdmann… - Atherosclerosis, 2023 - Elsevier
Sex differences in coronary artery disease (CAD) presentation, risk factors and prognosis
have been widely studied. Similarly, studies on atherosclerosis have shown prominent sex …

Genome-wide association studies and risk scores for coronary artery disease: sex biases

SG Byars, M Inouye - Sex-Specific Analysis of Cardiovascular Function, 2018 - Springer
Phenotypic sex differences in coronary artery disease (CAD) and its risk factors have been
apparent for many decades in basic and clinical research; however, whether these are also …

[HTML][HTML] Genetics of cardiovascular disease: importance of sex and ethnicity

SJ Winham, M de Andrade, VM Miller - Atherosclerosis, 2015 - Elsevier
Sex differences in incidence and prevalence of and morbidity and mortality from
cardiovascular disease are well documented. However, many studies examining the genetic …

Sexual differences in genetic predisposition of coronary artery disease

Y Huang, Q Hui, M Gwinn, YJ Hu… - Circulation: Genomic …, 2021 - Am Heart Assoc
Background: The genomic structure that contributes to the risk of coronary artery disease
(CAD) can be evaluated as a risk score of multiple variants. However, sex differences have …

Sex as a biological variable in atherosclerosis

JJ Man, JA Beckman, IZ Jaffe - Circulation research, 2020 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory vascular disease and the predominant cause of
heart attack and ischemic stroke. Despite the well-known sexual dimorphism in the …

Importance of sex and gender in atherosclerosis and cardiovascular disease

JD Spence, L Pilote - atherosclerosis, 2015 - atherosclerosis-journal.com
In this special issue of the journal, there are papers on bone health and coronary artery
calcification, age and sex differences in the effect of parental stroke on the progression of …

A scientific imperative as seen through a sharpened lens: sex, gender, and the cardiovascular condition

NA Bello, CN Bairey Merz, S Cheng - Circulation research, 2022 - Am Heart Assoc
Over the past 2 years, the coronavirus disease 2019 (COVID-19) pandemic has led us to
step back and reflect on our work as scientists through a new lens. This fresh perspective …

Sex-stratified gene regulatory networks reveal female key driver genes of atherosclerosis involved in smooth muscle cell phenotype switching

RJG Hartman, K Owsiany, L Ma, S Koplev, K Hao… - Circulation, 2021 - Am Heart Assoc
Background: Although sex differences in coronary artery disease are widely accepted with
women developing more stable atherosclerosis than men, the underlying pathobiology of …

Sex differences in coronary atherosclerosis

Y Sato, R Kawakami, A Sakamoto… - Current Atherosclerosis …, 2022 - Springer
Abstract Purpose of Review The importance of cardiovascular disease (CVD) in women has
long been underestimated. Therefore, we need to understand the impact of sex differences …

Sex-specific disparities in risk factors for coronary heart disease

SE Rosen, S Henry, R Bond, C Pearte… - Current atherosclerosis …, 2015 - Springer
In the past two decades, focused research on women at risk for cardiovascular disease
(CVD) has helped to clarify our understanding of some of the sex-specific factors that are …