Strategies for developing sensitive and specific nanoparticle-based lateral flow assays as point-of-care diagnostic device

JH Soh, HM Chan, JY Ying - Nano Today, 2020 - Elsevier
From a home-based pregnancy self-testing kit, lateral flow assays (LFAs) have proliferated
and gained widespread utilization as point-of-care (POC) test kits. Their prevalence is due to …

Toward next generation lateral flow assays: Integration of nanomaterials

A Sena-Torralba, R Álvarez-Diduk, C Parolo… - Chemical …, 2022 - ACS Publications
Lateral flow assays (LFAs) are currently the most used point-of-care sensors for both
diagnostic (eg, pregnancy test, COVID-19 monitoring) and environmental (eg, pesticides …

Challenges of the nano–bio interface in lateral flow and dipstick immunoassays

H de Puig, I Bosch, L Gehrke, K Hamad-Schifferli - Trends in biotechnology, 2017 - cell.com
Lateral flow assays (LFAs) are highly attractive for point-of-care (POC) diagnostics for
infectious disease, food safety, and many other medical uses. The unique optical, electronic …

Tutorial: design and fabrication of nanoparticle-based lateral-flow immunoassays

C Parolo, A Sena-Torralba, JF Bergua, E Calucho… - Nature protocols, 2020 - nature.com
Lateral-flow assays (LFAs) are quick, simple and cheap assays to analyze various samples
at the point of care or in the field, making them one of the most widespread biosensors …

Advances in nanoparticle‐based lateral flow immunoassay for point‐of‐care testing

D Lou, L Fan, T Jiang, Y Zhang - View, 2022 - Wiley Online Library
As a representative technology for point‐of‐care testing (POCT), lateral flow immunoassay
(LFIA) has been broadly used to detect analytes in many fields. However, its clinical …

Ultrasensitive and highly specific lateral flow assays for point-of-care diagnosis

Y Liu, L Zhan, Z Qin, J Sackrison, JC Bischof - ACS nano, 2021 - ACS Publications
Lateral flow assays (LFAs) are paper-based point-of-care (POC) diagnostic tools that are
widely used because of their low cost, ease of use, and rapid format. Unfortunately …

Recent developments of aptamer-based lateral flow assays for point-of-care (POC) diagnostics

A Jaisankar, S Krishnan, L Rangasamy - Analytical Biochemistry, 2022 - Elsevier
In the field of lateral flow assay (LFA), the application of aptamer as a bioreceptor has been
implemented to overcome the limitations of antibodies, such as tedious in vivo processes …

Lateral flow assay modified with time-delay wax barriers as a sensitivity and signal enhancement strategy

A Sena-Torralba, DB Ngo, C Parolo, L Hu… - Biosensors and …, 2020 - Elsevier
The ease of use, low cost and quick operation of lateral flow assays (LFA) have made them
some of the most common point of care biosensors in a variety of fields. However, their …

[HTML][HTML] Development of nucleic acid aptamer-based lateral flow assays: A robust platform for cost-effective point-of-care diagnosis

T Wang, L Chen, A Chikkanna, S Chen, I Brusius… - Theranostics, 2021 - ncbi.nlm.nih.gov
Lateral flow assay (LFA) has made a paradigm shift in the in vitro diagnosis field due to its
rapid turnaround time, ease of operation and exceptional affordability. Currently used LFAs …

Design of gold nanoparticle vertical flow assays for point-of-care testing

R Lei, D Wang, H Arain, C Mohan - Diagnostics, 2022 - mdpi.com
Vertical flow assays (VFAs) or flow-through assays have emerged as an alternate type of
paper-based assay due to their faster detection time, larger sample volume capacity, and …