[HTML][HTML] Coronavirus-induced host cubic membranes and lipid-related antiviral therapies: A focus on bioactive plasmalogens

Y Deng, A Angelova - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Coronaviruses have lipid envelopes required for their activity. The fact that coronavirus
infection provokes the formation of cubic membranes (CM)(denoted also as convoluted …

[HTML][HTML] The SARS-CoV2 envelope differs from host cells, exposes procoagulant lipids, and is disrupted in vivo by oral rinses

Z Saud, VJ Tyrrell, A Zaragkoulias, MB Protty… - Journal of Lipid …, 2022 - ASBMB
The lipid envelope of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an
essential component of the virus; however, its molecular composition is undetermined …

Lipid rafts as viral entry routes and immune platforms: A double-edged sword in SARS-CoV-2 infection?

R Roncato, J Angelini, A Pani, R Talotta - Biochimica et Biophysica Acta …, 2022 - Elsevier
Lipid rafts are nanoscopic compartments of cell membranes that serve a variety of biological
functions. They play a crucial role in viral infections, as enveloped viruses such as severe …

[HTML][HTML] The roles of lipids in SARS-CoV-2 viral replication and the host immune response

KN Theken, SY Tang, S Sengupta, GA FitzGerald - Journal of lipid research, 2021 - ASBMB
The significant morbidity and mortality associated with severe acute respiratory syndrome
coronavirus 2 infection has underscored the need for novel antiviral strategies. Lipids play …

[HTML][HTML] Role of specialized pro-resolving lipid mediators and their receptors in virus infection: a promising therapeutic strategy for SARS-CoV-2 cytokine storm

CH Lee - Archives of pharmacal research, 2021 - Springer
Unexpected viral infections outbreaks, significantly affect human health, leading to
increased mortality and life disruption. Among them is the severe acute respiratory …

[HTML][HTML] Anti-inflammatory and anti-viral actions of anionic pulmonary surfactant phospholipids

M Numata, DR Voelker - Biochimica et Biophysica Acta (BBA)-Molecular …, 2022 - Elsevier
Pulmonary surfactant is a mixture of lipids and proteins, consisting of 90% phospholipid, and
10% protein by weight, found predominantly in pulmonary alveoli of vertebrate lungs. Two …

Lipid storm within the lungs of severe COVID-19 patients: Extensive levels of cyclooxygenase and lipoxygenase-derived inflammatory metabolites

AS Archambault, Y Zaid, V Rakotoarivelo, É Doré… - MedRxiv, 2020 - medrxiv.org
ABSTRACT BACKGROUND Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-
2) is the infectious agent responsible for Coronavirus disease 2019 (COVID-19). While …

[HTML][HTML] Coronaviruses, cholesterol and statins: Involvement and application for Covid-19

S Orlowski, JJ Mourad, A Gallo, E Bruckert - Biochimie, 2021 - Elsevier
The infectious power of coronaviruses is dependent on cholesterol present in the
membranes of their target cells. Indeed, the virus enters the infected cell either by fusion or …

Mapping the Lipid Signatures in COVID-19 Infection: Diagnostic and Therapeutic Solutions

A Dasgupta, S Gangai, R Narayan… - Journal of Medicinal …, 2023 - ACS Publications
The COVID-19 pandemic ignited research centered around the identification of robust
biomarkers and therapeutic targets. SARS-CoV-2, the virus responsible, hijacks the …

[HTML][HTML] Serum lipid mediator profiles in COVID-19 patients and lung disease severity: a pilot study

P Irún, R Gracia, E Piazuelo, J Pardo, E Morte… - Scientific Reports, 2023 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is highly
heterogeneous, ranging from asymptomatic to severe and fatal cases. COVID-19 has been …