Long noncoding RNAs in cancer metastasis

SJ Liu, HX Dang, DA Lim, FY Feng… - Nature Reviews Cancer, 2021 - nature.com
Metastasis is a major contributor to cancer-associated deaths. It is characterized by a
multistep process that occurs through the acquisition of molecular and phenotypic changes …

[HTML][HTML] An emerging role for long non-coding RNAs in cancer metastasis

JT Serviss, P Johnsson, D Grandér - Frontiers in genetics, 2014 - frontiersin.org
Metastasis is a multistep process beginning with the dissemination of tumor cells from a
primary site and leading to secondary tumor development in an anatomically distant …

Long non-coding RNAs and cancer metastasis: Molecular basis and therapeutic implications

H Ming, B Li, L Zhou, A Goel, C Huang - Biochimica et Biophysica Acta …, 2021 - Elsevier
Cancer metastasis, defined by the epithelial to mesenchymal transition (EMT) of tumor cells,
disseminates from the primary site to progressively colonize in distant tissues, and accounts …

From biomarkers to therapeutic targets—the promises and perils of long non-coding RNAs in cancer

T Gutschner, G Richtig, M Haemmerle… - Cancer and Metastasis …, 2018 - Springer
Biomarker-driven personalized cancer therapy is a field of growing interest, and several
molecular tests have been developed to detect biomarkers that predict, eg, response of …

Molecular mechanisms of long noncoding RNAs‐mediated cancer metastasis

Y Li, SD Egranov, L Yang, C Lin - Genes, Chromosomes and …, 2019 - Wiley Online Library
Cancer metastasis is a multistep process that requires cancer cells to leave the primary site,
survive in the blood stream, and finally colonize at a distant organ. It is the major cause of …

Long non-coding RNAs and their role in metastasis

UH Weidle, F Birzele, G Kollmorgen… - Cancer genomics & …, 2017 - cgp.iiarjournals.org
The perception of long non-coding RNAs as chunk RNA and transcriptional noise has been
steadily replaced by their role as validated targets for a diverse set of physiological …

From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis

S Dhamija, S Diederichs - International journal of cancer, 2016 - Wiley Online Library
Metastasis is a multistep process that involves the dissemination of cells from the primary
tumor and colonization of distant secondary organs. Epithelial cells at the invasive front of a …

[HTML][HTML] Long noncoding RNAs in cancer: mechanisms of action and technological advancements

N Bartonicek, JLV Maag, ME Dinger - Molecular cancer, 2016 - Springer
The previous decade has seen long non-coding RNAs (lncRNAs) rise from obscurity to
being defined as a category of genetic elements, leaving its mark on the field of cancer …

[HTML][HTML] Long non-coding RNAs: potential new biomarkers for predicting tumor invasion and metastasis

C Jiang, X Li, H Zhao, H Liu - Molecular cancer, 2016 - Springer
Long non-coding RNAs (lncRNAs) play important roles in malignant neoplasia. Indeed,
many hallmarks of cancer define that the malignant phenotype of tumor cells are controlled …

[HTML][HTML] Long non-coding RNA regulation of epithelial–mesenchymal transition in cancer metastasis

Q Xu, F Deng, Y Qin, Z Zhao, Z Wu, Z Xing, A Ji… - Cell death & …, 2016 - nature.com
Metastasis is a multistep process starting with the dissemination of tumor cells from a
primary site and ending with secondary tumor development in an anatomically distant …