Suppression of obesity and inflammation by polysaccharide from sporoderm-broken spore of Ganoderma lucidum via gut microbiota regulation

T Sang, C Guo, D Guo, J Wu, Y Wang, Y Wang… - Carbohydrate …, 2021 - Elsevier
Ganoderma lucidum has been shown to have anti-obesity effects. However, polysaccharide
extracted from the sporoderm-broken spores of Ganoderma lucidum (BSGLP) against …

Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon

C Guo, D Guo, L Fang, T Sang, J Wu, C Guo… - Carbohydrate …, 2021 - Elsevier
This study investigated the effects of water-soluble polysaccharide extracted from the
sporoderm-removed spores of Ganoderma lucidum (GLP) against AOM/DSS-induced …

Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota

CJ Chang, CS Lin, CC Lu, J Martel, YF Ko… - Nature …, 2015 - nature.com
Obesity is associated with low-grade chronic inflammation and intestinal dysbiosis.
Ganoderma lucidum is a medicinal mushroom used in traditional Chinese medicine with …

Polysaccharide peptides from Ganoderma lucidum ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet-fed rats

XC Lv, WL Guo, L Li, XD Yu, B Liu - Journal of Functional Foods, 2019 - Elsevier
This study aimed to investigate the effects of polysaccharide peptides from Ganoderma
lucidum (GLPP) on hyperlipidaemia and gut microbiota dysbiosis in high-fat diet (HFD) …

Ganoderma lucidum polysaccharides improve insulin sensitivity by regulating inflammatory cytokines and gut microbiota composition in mice

S Xu, Y Dou, B Ye, Q Wu, Y Wang, M Hu, F Ma… - Journal of Functional …, 2017 - Elsevier
Ectopic lipid accumulation and low-grade chronic inflammation are critical pathogenesis of
insulin resistance development. Ganoderma lucidum is a traditional Chinese herb for …

Ganoderma lucidum polysaccharide alleviating colorectal cancer by alteration of special gut bacteria and regulation of gene expression of colonic epithelial cells

J Luo, C Zhang, R Liu, L Gao, S Ou, L Liu… - Journal of Functional …, 2018 - Elsevier
It is still uncertain whether the consumption of Ganoderma lucidum polysaccharides (GLPs)
alleviates the colorectal cancer (CRC) through gut microbiota. In this study, we investigated …

Ganoderma polysaccharide and chitosan synergistically ameliorate lipid metabolic disorders and modulate gut microbiota composition in high fat diet‐fed golden …

AJ Tong, RK Hu, LX Wu, XC Lv, X Li… - Journal of food …, 2020 - Wiley Online Library
High‐fat diet (HFD) and sucrose intake can lead to hyperlipidemia, hypercholesterolemia,
and nonalcoholic fatty liver disease (NAFLD) as well as disturbed gastrointestinal microbiota …

Intake of Ganoderma lucidum polysaccharides reverses the disturbed gut microbiota and metabolism in type 2 diabetic rats

M Chen, D Xiao, W Liu, Y Song, B Zou, L Li, P Li… - International journal of …, 2020 - Elsevier
Ganoderma lucidum polysaccharides (GLP), a kind of medicinal mushrooms, were widely
used in southeastern countries with putative anti-diabetic effects. In order to unravel the …

[HTML][HTML] Ganoderma lucidum polysaccharide improves rat DSS-induced colitis by altering cecal microbiota and gene expression of colonic epithelial cells

J Xie, Y Liu, B Chen, G Zhang, S Ou, J Luo… - Food & Nutrition …, 2019 - ncbi.nlm.nih.gov
Background The effects of β-glucan on colitis mice are contradictory in previous reports. As a
result, it is still unclear whether there is an anti-colitis effect in Ganoderma lucidum …

A polysaccharide isolated from Ganoderma lucidum ameliorates hyperglycemia through modulating gut microbiota in type 2 diabetic mice

W Shao, C Xiao, T Yong, Y Zhang, H Hu, T Xie… - International Journal of …, 2022 - Elsevier
In this study, we reported a thermal stable and non-toxic heteropolysaccharide F31, which
decreased the blood glucose of diabetic mice (21.75 mmol/L) induced by high-fat diet (HFD) …