The immune system is able to respond more vigorously to the second contact with a given
antigen than to the first contact. Vaccination protocols generally include at least two doses …

The immune system is inordinately complex with many interacting components determining
overall outcomes. Mathematical and computational modelling provides a useful way in …

Cancer immunotherapy aims at eliciting an immune system response against the tumor.
However, it is often characterized by toxic side-effects. Limiting the tumor growth and …

With major advances in experimental techniques to track antigen-specific immune
responses many basic questions on the kinetics of virus-specific immunity in humans remain …

We have developed a spatial–temporal mathematical model (PDE) to capture fundamental
aspects of the immune response to antigen. We have considered terms that broadly …

One of the significant challenges in biomathematics (and other areas of science) is to
formulate meaningful mathematical models. Our problem is to decide on a parametrized …

In order to formulate quantitatively correct mathematical models of the immune system, one
requires an understanding of immune processes and familiarity with a range of …

We formulate and analyse a mathematical model describing immune response to avascular
tumour under the influence of immunotherapy and chemotherapy and their combinations as …

Abstract Background We introduce the Basic Immune Simulator (BIS), an agent-based
model created to study the interactions between the cells of the innate and adaptive immune …

Many immue-inspired algorithms are based on the abstractions of one or several
immunology theories, such as clonal selection, negative selection, positive selection, rather …