Genistein encapsulated inulin-stearic acid bioconjugate nanoparticles: Formulation development, characterization and anticancer activity

AK Jangid, R Solanki, S Patel, D Pooja… - International Journal of …, 2022 - Elsevier
Achieving controlled and site-specific delivery of hydrophobic drugs in the colon
environment is a major challenge. The primary goal of this research was to synthesize inulin …

Heparin appended ADH-anionic polysaccharide nanoparticles for site-specific delivery of usnic acid

A Garg, S Garg, NK Sahu, S Rani, U Gupta… - International journal of …, 2019 - Elsevier
The intention of present research work is to formulate usnic acid (UA) loaded heparin
modified gellan gum (HAG) nanoparticles (NPs). HAG copolymer based conjugation was …

Phenyl boronic acid-PEG-stearic acid biomaterial-based and sialic acid targeted nanomicelles for colon cancer treatment

AK Jangid, R Solanki, M Jadav, S Bora, S Patel… - Colloids and Surfaces A …, 2023 - Elsevier
This study aims to develop and evaluate a sialic acid receptor-targeting biomaterial for an
effective delivery of usnic acid (UA). The novel biomaterial system is composed of three …

Fabrication of genistein-loaded biodegradable TPGS-b-PCL nanoparticles for improved therapeutic effects in cervical cancer cells

H Zhang, G Liu, X Zeng, Y Wu, C Yang… - International Journal …, 2015 - Taylor & Francis
Genistein is one of the most studied isoflavonoids with potential antitumor efficacy, but its
poor water solubility limits its clinical application. Nanoparticles (NPs), especially …

Purification and characterization of a chicory polysaccharide and its application in stabilizing genistein for cancer therapy

L Shi, Z Lin, J Hou, W Liu, J Xu, Y Guo - International Journal of Biological …, 2023 - Elsevier
Genistein is an isoflavone with chemopreventive and therapeutic effects on various types of
cancers. Apparently, in contrast to the advantages of multi-target therapy, the poor water …

New method and characterization of self-assembled gelatin–oleic nanoparticles using a desolvation method via carbodiimide/N-hydroxysuccinimide (EDC/NHS) …

C Park, CLN Vo, T Kang, E Oh, BJ Lee - European Journal of …, 2015 - Elsevier
In this study, we investigated a new method for the preparation of gelatin–oleic conjugate
(GOC) as an amphiphilic biomaterial to load model anti-cancer drugs into self-assembled …

Sialic acid conjugated chitosan nanoparticles: modulation to target tumour cells and therapeutic opportunities

R Rana, S Rani, V Kumar, KT Nakhate, Ajazuddin… - AAPS …, 2021 - Springer
Targeted delivery of therapeutics forestalls the dreadful delocalized effects, drug toxicities
and needless immunosuppression. Cancer cells are bounteous with sialic acid and the …

Angelica sinensis polysaccharide nanoparticles as a targeted drug delivery system for enhanced therapy of liver cancer

Y Zhang, Z Cui, H Mei, J Xu, T Zhou, F Cheng… - Carbohydrate …, 2019 - Elsevier
In recent years, the utilization of polysaccharides as targeted drug carriers has attracted
considerable attention. Herein, Angelica sinensis polysaccharide (ASP), a plant …

Folate-targeted nanomicelles containing silibinin as an active drug delivery system for liver cancer therapy

V Ghalehkhondabi, M Soleymani, A Fazlali - Journal of Drug Delivery …, 2021 - Elsevier
The majority of herbal anticancer drugs are insoluble in water or become unstable during
their transport to tumor tissues, hence they require a special drug delivery system. The main …

Disulfide-bridged chitosan-eudragit S-100 nanoparticles for colorectal cancer

A Sood, A Dev, SJ Mohanbhai, N Shrimali… - ACS Applied Nano …, 2019 - ACS Publications
Covalently bonded Eudragit S-100 (EU) and chitosan (CS) based colon-specific
nanoparticles (CSE NPs) were fabricated as drug carriers for treating colorectal cancers …