Ethnic differences between Asians and non-Asians in clustering-based phenotype classification of adult-onset diabetes mellitus: a systematic narrative review

JS Varghese, KMV Narayan - Primary care diabetes, 2022 - Elsevier
Several international studies have stratified people with diabetes into phenotypical clusters.
However, there has not been a systematic examination of the variation in these clusters …

Subgroups of adult-onset diabetes: a data-driven cluster analysis in a Ghanaian population

I Danquah, I Mank, CS Hampe, KAC Meeks… - Scientific reports, 2023 - nature.com
Adult-onset diabetes mellitus (here: aDM) is not a uniform disease entity. In European
populations, five diabetes subgroups have been identified by cluster analysis using simple …

Phenotypic clusters of type 2 diabetes mellitus among North Indians reveal higher levels of insulin deficiency along with insulin resistance

I Arora, N Raizada, M Aslam, S Madhu - Diabetes & Metabolic Syndrome …, 2024 - Elsevier
Background Type 2 diabetes is now considered a heterogenous disease. Distinct clusters
have been identified with patterns varying between Europeans and South Asians as well as …

Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study

RC Slieker, LA Donnelly, H Fitipaldi, GA Bouland… - Diabetologia, 2021 - Springer
Aims/hypothesis Five clusters based on clinical characteristics have been suggested as
diabetes subtypes: one autoimmune and four subtypes of type 2 diabetes. In the current …

Novel subgroups and chronic complications of diabetes in middle-aged and elderly Chinese: a prospective cohort study

F Wang, R Zheng, L Li, M Xu, J Lu, Z Zhao… - Frontiers in …, 2022 - frontiersin.org
Background Diabetes mellitus, especially type 2 diabetes mellitus (T2DM), is regarded as
highly heterogeneous. Novel diabetes phenotypes by cluster analysis have been proposed …

Identification of two novel subgroups in patients with diabetes mellitus and their association with clinical outcomes: A two‐step cluster analysis

X Xiong, Y Yang, L Wei, Y Xiao, L Li… - Journal of Diabetes …, 2021 - Wiley Online Library
Abstract Aims/Introduction The aim of this study was to determine whether distinct
subphenotypes of patients with type 2 diabetes in the European classification exist in …

Factors associated with risk of diabetic complications in novel cluster-based diabetes subgroups: a Japanese retrospective cohort study

H Tanabe, H Saito, A Kudo, N Machii, H Hirai… - Journal of clinical …, 2020 - mdpi.com
Diabetes is a complex and heterogeneous disease, making the prediction of the risks of
diabetic complications challenging. Novel adult-onset diabetes subgroups have been …

The identification of diabetes mellitus subtypes applying cluster analysis techniques: a systematic review

A Sarría-Santamera, B Orazumbekova… - International Journal of …, 2020 - mdpi.com
Diabetes Mellitus is a chronic and lifelong disease that incurs a huge burden to healthcare
systems. Its prevalence is on the rise worldwide. Diabetes is more complex than the …

Subtypes of type 2 diabetes and their association with outcomes in Korean adults-a cluster analysis of community-based prospective cohort

YC Hwang, HY Ahn, JE Jun, IK Jeong, KJ Ahn… - Metabolism, 2023 - Elsevier
Background Little is known about the subtypes of type 2 diabetes (T2D) and their
association with clinical outcomes in Asians. Methods We performed data-driven cluster …

A novel diabetes typology: towards precision diabetology from pathogenesis to treatment

C Herder, M Roden - Diabetologia, 2022 - Springer
The current classification of diabetes, based on hyperglycaemia, islet-directed antibodies
and some insufficiently defined clinical features, does not reflect differences in aetiological …