The secretome of mesenchymal stem cells and oxidative stress: challenges and opportunities in cell-free regenerative medicine

B Rahimi, M Panahi, N Saraygord-Afshari… - Molecular Biology …, 2021 - Springer
Over the last decade, mesenchymal stem cells (MSCs) have been considered a suitable
source for cell-based therapy, especially in regenerative medicine. First, the efficacy and …

[HTML][HTML] Mesenchymal stem cells secretome: The cornerstone of cell-free regenerative medicine

A González-González, D García-Sánchez… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are the most frequently used stem cells in clinical trials due
to their easy isolation from various adult tissues, their ability of homing to injury sites and …

Insights into the secretome of mesenchymal stem cells and its potential applications

S Eleuteri, A Fierabracci - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) have regenerative, immunoregulatory properties and can
be easily isolated and expanded in vitro. Despite being a powerful tool for clinical …

Senescence induces fundamental changes in the secretome of mesenchymal stromal cells (MSCs): implications for the therapeutic use of MSCs and their derivates

Y Siraj, U Galderisi, N Alessio - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Mesenchymal stromal cells (MSCs) are a heterogeneous population containing multipotent
adult stem cells with a multi-lineage differentiation capacity, which differentiated into …

Mesenchymal stem cells in homeostasis and systemic diseases: hypothesis, evidences, and therapeutic opportunities

FJ Vizoso, N Eiro, L Costa, P Esparza… - International journal of …, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) are present in all organs and tissues, playing a well-known
function in tissue regeneration. However, there is also evidence indicating a broader role of …

The mesenchymal stem cell secretome: A new paradigm towards cell-free therapeutic mode in regenerative medicine

P Kumar, S Kandoi, R Misra, S Vijayalakshmi… - Cytokine & growth factor …, 2019 - Elsevier
Abstract Mesenchymal Stem Cells (MSCs) have been shown to be a promising candidate for
cell-based therapy. The therapeutic potential of MSCs, towards tissue repair and wound …

Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?

FG Teixeira, MM Carvalho, N Sousa… - Cellular and Molecular …, 2013 - Springer
The low regeneration potential of the central nervous system (CNS) represents a challenge
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …

The current landscape of the mesenchymal stromal cell secretome: a new paradigm for cell-free regeneration

VBR Konala, MK Mamidi, R Bhonde, AK Das… - Cytotherapy, 2016 - Elsevier
The unique properties of mesenchymal stromal/stem cells (MSCs) to self-renew and their
multipotentiality have rendered them attractive to researchers and clinicians. In addition to …

Pretreated mesenchymal stem cells and their secretome: enhanced immunotherapeutic strategies

Y Su, C Xu, W Cheng, Y Zhao, L Sui… - International journal of …, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) with self-renewing, multilineage differentiation and
immunomodulatory properties, have been extensively studied in the field of regenerative …

The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …