Thermosensitive Polyurethane-Based Hydrogels as Potential Vehicles for Meloxicam Delivery

IA Plugariu, LM Gradinaru, M Avadanei, I Rosca… - Pharmaceuticals, 2023 - mdpi.com
Meloxicam (MX) is a nonsteroidal anti-inflammatory drug (NSAID) used mainly to reduce
pain, inflammation, and fever. In the present study, thermosensitive polyurethane (PU) …

Thermosensitive micellar hydrogels as vehicles to deliver drugs with different wettability

R Laurano, M Boffito - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
The design of adaptable drug delivery systems able to encapsulate and release drugs with
different wettability has been attracting widespread interest. Additionally, many attempts …

Preparation of Supramolecular Hydrogels Containing Poloxamers and methyl-β-cyclodextrin

M Joao Garcia, J Ruivo, R Oliveira… - Letters in Drug Design …, 2014 - ingentaconnect.com
Meloxicam is a non-steroidal anti-inflammatory drug used in the treatment of rheumatoid
arthritis, osteoarthritis and other inflammatory diseases. However, its prolonged use is …

Semi-Crystalline copolymer hydrogels as smart drug carriers: In vitro thermo-responsive naproxen release study

S Ilić-Stojanović, L Nikolić, V Nikolić, S Petrović, V Oro… - Pharmaceutics, 2021 - mdpi.com
In this study, poly (N-isopropylacrylamide-co-2-hydroxypropyl methacrylate) hydrogels were
synthesized using free radical initiated copolymerization method. Four hydrogels with …

[HTML][HTML] In vitro and in vivo applications of a universal and synthetic thermo-responsive drug delivery hydrogel platform

H Gholizadeh, E Landh, DM Silva, A Granata… - International Journal of …, 2023 - Elsevier
A synthetic and thermo-responsive polymer, poly (N-isopropylacrylamide)-co-(polylactide/2-
hydroxy methacrylate)-co-(oligo (ethylene glycol)), is used to formulate a universal carrier …

Rheological characteristics of novel meloxicam-loaded complex organogels based on fumed silica and poloxamer

T Osmalek, A Froelich, B Jadach… - Current Drug …, 2018 - ingentaconnect.com
Background: Meloxicam is a non-steroidal anti-inflammatory drug revealing poor solubility in
water and good permeability through biological membranes. It is currently administered …

A thermo-responsive polyurethane organogel for norfloxacin delivery

DE Liu, Q Chen, YB Long, J Ma, H Gao - Polymer Chemistry, 2018 - pubs.rsc.org
To overcome the constraints presented by the conventional hydrogel-based skin patch,
including poor transdermal penetration activity and reluctant release of the encapsulated …

Amphiphilic polyurethane hydrogels as smart carriers for acidic hydrophobic drugs

LP Fonseca, RB Trinca, MI Felisberti - International journal of …, 2018 - Elsevier
Amphiphilic hydrogels are widely reported as systems with great potential for controlled drug
release. Nevertheless, the majority of studies make use of functionalization or attachment of …

Development of hot-melt extruded drug/polymer matrices for sustained delivery of meloxicam

YC Chen, DE Moseson, CA Richard… - Journal of Controlled …, 2022 - Elsevier
For effective resolution of regional subacute inflammation and prevention of biofouling
formation, we have developed a polymeric implant that can release meloxicam, a selective …

Topical Meloxicam Hydroxypropyl Guar Hydrogels Based on Low-Substituted Hydroxypropyl Cellulose Solid Dispersions

Z Dahma, C Torrado-Salmerón, C Álvarez-Álvarez… - Gels, 2024 - mdpi.com
Meloxicam (MX) is a poorly water-soluble drug with severe gastrointestinal side effects.
Topical hydrogel of hydroxypropyl guar (HPG) was formulated using a solid dispersion (SD) …