Alzheimer's disease and related dementias (ADRD) are among the top contributors to
disability and mortality in later life. As with many chronic conditions, aging is the single most …

A rapidly ageing population and a limited therapeutic toolbox urgently necessitate new
approaches to treat neurodegenerative diseases. Brain ageing, the key risk factor for …

Aging is a major risk factor for a number of chronic diseases, including neurodegenerative
and cerebrovascular disorders. Aging processes have therefore been discussed as potential …

New discoveries challenge the long-held view that aging is characterized by progressive
loss and decline. Evidence for functional reorganization, compensation and effective …

Aging is the leading risk factor for most chronic illnesses of old age, including Alzheimer
disease (AD), a progressive neurodegenerative disease with currently no therapies that …

With an increasingly ageing population that is expected to double by 2050 in the US, it is
paramount that we further understand the neurological changes that occur during ageing …

Dementia, particularly Alzheimer's disease (AD), is a growing pandemic that presents
profound challenges to healthcare systems, families, and societies throughout the world. By …

Aging is accompanied by cognitive decline in a major segment of the population and is the
primary risk factor for Alzheimer's disease and other prevalent neurodegenerative disorders …

The aging brain is shaped by many structural and functional alterations. Recent cross-
disciplinary efforts have uncovered powerful and integrated adaptive mechanisms that …

As more people live longer, age-related neurodegenerative diseases are an increasingly
important societal health issue. Treatments targeting specific pathologies such as amyloid …