INTRODUCTION Multiple sclerosis (MS) is an inflammatory and degenerative disease of the
central nervous system (CNS) that often presents in young adults. Over the past decade …

We assembled and analyzed genetic data of 47,351 multiple sclerosis (MS) subjects and
68,284 control subjects and establish a reference map of the genetic architecture of MS that …

Multiple sclerosis (MS) is a common autoimmune disease that targets myelin in the central
nervous system (CNS). Multiple genome-wide association studies (GWAS) over the past 10 …

Genome-wide association studies (GWAS) have identified more than 50,000 unique
associations with common human traits. While this represents a substantial step forward …

A broad scientific consensus has emerged linking multiple sclerosis (MS) risk to multiple
independent and interacting DNA variants that are relatively frequent in the population and …

Multiple sclerosis (MS) is an autoimmune disease that represents a primary cause of
neurological disability in the young adult population. Converging evidence supports the …

Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …

Multiple sclerosis (MS) is a common and severe CNS disorder that is characterized by
myelin loss, chronic inflammation, axonal and oligodendrocyte pathology, and progressive …

Multiple sclerosis is a common disease of the central nervous system in which the interplay
between inflammatory and neurodegenerative processes typically results in intermittent …

Multiple sclerosis is a complex neurological disease, with∼ 20% of risk heritability
attributable to common genetic variants, including> 230 identified by genome-wide …