Cerium oxide nanoparticles: a 'radical'approach to neurodegenerative disease treatment

S Naz, J Beach, B Heckert, T Tummala… - …, 2017 - Taylor & Francis
Despite advances in understanding the factors that cause many neurodegenerative
diseases (NDs), no current therapies have yielded significant results. Cerium oxide …

Cerium oxide nanoparticles in neuroprotection and considerations for efficacy and safety

BA Rzigalinski, CS Carfagna… - Wiley Interdisciplinary …, 2017 - Wiley Online Library
Cerium oxide nanoparticles have widespread use in the materials industry, and have
recently come into consideration for biomedical use due to their potent regenerative …

The potential of cerium oxide nanoparticles (nanoceria) for neurodegenerative disease therapy

AY Estevez, JS Erlichman - Nanomedicine, 2014 - Taylor & Francis
Editorial Estevez & Erlichman effects of cerium oxide nanoparticles have been reported in
various model systems [11, 12], and this would be cause for concern if the ultimate goal is to …

Cerium oxide nanoparticles for the treatment of neurological oxidative stress diseases

AY Estevez, JS Erlichman - Oxidative Stress: Diagnostics …, 2011 - ACS Publications
Due to their potent free radical scavenging properties, cerium oxide (CeO2) nanoparticles
(nanoceria) are widely used as catalysts in industrial applications. However, given the …

Treatment of neurodegenerative disorders with radical nanomedicine

N Singh, CA Cohen… - Annals of the New York …, 2007 - Wiley Online Library
In engineering and materials science, nanotechnology has provided many advances that
effectively reduce oxidative damage generated by free radical production. Despite such …

Cerium oxide nanoparticles: green synthesis and biological applications

F Charbgoo, MB Ahmad, M Darroudi - International journal of …, 2017 - Taylor & Francis
CeO2 nanoparticles (NPs) have shown promising approaches as therapeutic agents in
biology and medical sciences. The physicochemical properties of CeO2-NPs, such as size …

Cerium oxide nanoparticles trigger neuronal survival in a human Alzheimer disease model by modulating BDNF pathway

B D'Angelo, S Santucci, E Benedetti… - Current …, 2009 - ingentaconnect.com
In engineering and materials science, nanotechnology has made significant advances in the
reduction of free radical damage. Despite such advances, there has been little application to …

Europium-doped cerium oxide nanoparticles for microglial amyloid beta clearance and homeostasis

J Machhi, P Yeapuri, M Markovic, M Patel… - ACS chemical …, 2022 - ACS Publications
Alzheimer's disease (AD) is the most common neurodegenerative disorder. Pathologically,
the disease is characterized by the deposition of amyloid beta (Aβ) plaques and the …

[HTML][HTML] Cerium oxide nanoparticles: potential applications for cancer and other diseases

MS Wason, J Zhao - American journal of translational research, 2013 - ncbi.nlm.nih.gov
The diverse abilities of cerium oxide nanoparticles (CONPs) have encouraged researchers
to pursue CONPs as a therapeutic agent to treat a number of diseases, including cancer. In …

Custom cerium oxide nanoparticles protect against a free radical mediated autoimmune degenerative disease in the brain

KL Heckman, W DeCoteau, A Estevez, KJ Reed… - ACS …, 2013 - ACS Publications
Cerium oxide nanoparticles are potent antioxidants, based on their ability to either donate or
receive electrons as they alternate between the+ 3 and+ 4 valence states. The dual …