CAR, mGPS and hs-mGPS: What is among them the best gero-biomarker for age-related diseases? And for what clinical application?

M Carella, D Magro, L Scola, C Pisano, E Guida… - Mechanisms of Ageing …, 2024 - Elsevier
The identification of biomarkers linked to the onset, progression, and prevention of age-
related diseases (ARD), in the era of personalized medicine, represents the best goal of …

Revisiting the hallmarks of aging to identify markers of biological age

F Guerville, P De Souto Barreto, I Ader… - The Journal of …, 2020 - Springer
The Geroscience aims at a better understanding of the biological processes of aging, to
prevent and/or delay the onset of chronic diseases and disability as well as to reduce the …

[图书][B] Biomarkers of human aging

A Moskalev - 2019 - Springer
In laboratory studies, potential geroprotective interventions have been created: more than
400 geroprotectors, several gene and cell therapies. Their translation into medical practice …

From Geroscience Discoveries to Public Health Practice: Shifting the Paradigm towards Healthy Ageing

A Csiszar, R Adany, S Tarantini… - European Journal of …, 2023 - academic.oup.com
The global population is ageing rapidly, and the paradigm towards healthy ageing is shifting
from a challenge to an opportunity. Advances in geroscience have shown promise in …

The continuum of aging and age-related diseases: common mechanisms but different rates

C Franceschi, P Garagnani, C Morsiani, M Conte… - Frontiers in …, 2018 - frontiersin.org
Geroscience, the new interdisciplinary field that aims to understand the relationship between
aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on …

BIOMARKERS OF HUMAN AGING

R Kohanski - Innovation in Aging, 2017 - europepmc.org
The Geroscience hypothesis states that slowing the rate of aging will delay the onset and/or
reduce severity of aging-related diseases without necessarily altering life span, thus …

Biomarkers of ageing: Current state‐of‐art, challenges, and opportunities

R Chen, Y Wang, S Zhang, G Bulloch… - MedComm–Future …, 2023 - Wiley Online Library
Given the unprecedented phenomenon of population ageing, studies have increasing
captured the heterogeneity within the ageing process. In this context, the concept of …

[HTML][HTML] Biomarkers of Aging and Relevant Evaluation Techniques: A Comprehensive Review

X Tao, Z Zhu, L Wang, C Li, L Sun, W Wang… - Aging and …, 2024 - ncbi.nlm.nih.gov
The risk of developing chronic illnesses and disabilities is increasing with age. To predict
and prevent aging, biomarkers relevant to the aging process must be identified. This paper …

[HTML][HTML] Biomarker development for translational geroscience: Considerations for a strategic framework focusing on early clinical development

JL Sanders - Aging Cell, 2023 - ncbi.nlm.nih.gov
The expectation that geroscience will allow humans to age optimally continues to generate
excitement among a growing community of professionals and non-professionals, including …

Advances and challenges in geroscience research: an update

A Yabluchanskiy, Z Ungvari, A Csiszar… - Physiology …, 2018 - akjournals.com
Aging remains the most pervasive risk factor for a wide range of chronic diseases that afflict
modern societies. In the United States alone, incidence of age-related diseases (eg …