Dysfunctional phenotype of systemic and pulmonary regulatory T cells associate with lethal COVID‐19 cases

MH Gonçalves‐Pereira, L Santiago, CG Ravetti… - …, 2023 - Wiley Online Library
Severe cases of COVID‐19 present hyperinflammatory condition that can be fatal. Little is
known about the role of regulatory responses in SARS‐CoV‐2 infection. In this study, we …

Distinctive dynamics and functions of the CD4+ CD25+ FOXP3+ regulatory T cell population in patients with severe and mild COVID-19

H Nam, JY Koh, JH Jung, H Jeong… - The Journal of …, 2023 - journals.aai.org
Although CD4+CD25+FOXP3+ regulatory T (TREG) cells have been studied in patients with
COVID-19, changes in the TREG cell population have not been longitudinally examined …

Toward an understanding of regulatory T cells in COVID‐19: a systematic review

M Rahimzadeh, N Naderi - Journal of Medical Virology, 2021 - Wiley Online Library
A more detailed understanding of Treg cells in COVID‐19 infection will broaden our
knowledge of the COVID‐19 immunopathology and give us more insight into the curative …

Differential regulatory T cell signature after recovery from mild COVID-19

PH de Sousa Palmeira, RF Peixoto… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by a range
of symptoms in which host immune response have been associated with disease …

[HTML][HTML] Regulatory T cells in COVID-19

H Wang, Z Wang, W Cao, Q Wu, Y Yuan… - Aging and …, 2021 - ncbi.nlm.nih.gov
The outbreak of coronavirus disease 2019 (COVID-19) is caused by the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which leads to the disruption of …

Regulatory T cells in immunopathogenesis and severity of COVID-19: A systematic review

S Alahyari, M Rajaeinejad, H Jalaeikhoo… - Archives of Iranian …, 2022 - journalaim.com
Background: Severe cases of coronavirus disease 2019 (COVID-19) often experience hyper-
inflammatory reactions, acute respiratory distress syndrome (ARDS), blood clotting, and …

A scoping review of regulatory T cell dynamics in convalescent COVID-19 patients–indications for their potential involvement in the development of Long COVID?

S Haunhorst, W Bloch, F Javelle, K Krüger… - Frontiers in …, 2022 - frontiersin.org
Background Recovery from coronavirus disease 2019 (COVID-19) can be impaired by the
persistence of symptoms or new-onset health complications, commonly referred to as Long …

[HTML][HTML] The role of CD4+ FoxP3+ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment

Y Wang, J Zheng, MS Islam, Y Yang… - International journal of …, 2021 - ncbi.nlm.nih.gov
The severe cases of Coronavirus Disease 2019 (COVID-19) frequently exhibit excessive
inflammatory responses, acute respiratory distress syndrome (ARDS), coagulopathy, and …

Regulatory T cells decreased during recovery from mild covid-19

P Seepathomnarong, J Ongarj, R Sophonmanee… - Viruses, 2022 - mdpi.com
Depending on the intensity and duration of SARS-CoV-2 infection, the host immune
response plays a significant role in immunological protection. Here, we studied the …

Immunosuppression as a hallmark of critical COVID-19: prospective study

E Kalicińska, D Szymczak, A Zińczuk, B Adamik… - Cells, 2021 - mdpi.com
The dysregulation of both the innate and adaptive responses to SARS-CoV-2 have an
impact on the course of COVID-19, and play a role in the clinical outcome of the disease …