Brain age vector: A measure of brain aging with enhanced neurodegenerative disorder specificity

C Ran, Y Yang, C Ye, H Lv, T Ma - Human brain mapping, 2022 - Wiley Online Library
Neuroimaging‐driven brain age estimation has become popular in measuring brain aging
and identifying neurodegenerations. However, the single estimated brain age (gap) …

Predicting brain-age from multimodal imaging data captures cognitive impairment

F Liem, G Varoquaux, J Kynast, F Beyer, SK Masouleh… - Neuroimage, 2017 - Elsevier
The disparity between the chronological age of an individual and their brain-age measured
based on biological information has the potential to offer clinically relevant biomarkers of …

Mind the gap: Performance metric evaluation in brain‐age prediction

AMG de Lange, M Anatürk, J Rokicki… - Human Brain …, 2022 - Wiley Online Library
Estimating age based on neuroimaging‐derived data has become a popular approach to
developing markers for brain integrity and health. While a variety of machine‐learning …

[HTML][HTML] T1-weighted MRI-driven brain age estimation in Alzheimer's disease and Parkinson's disease

I Beheshti, S Mishra, D Sone, P Khanna… - Aging and …, 2020 - ncbi.nlm.nih.gov
Neuroimaging-driven brain age estimation has introduced a robust (reliable and heritable)
biomarker for detecting and monitoring neurodegenerative diseases. Here, we computed …

Investigating the temporal pattern of neuroimaging-based brain age estimation as a biomarker for Alzheimer's Disease related neurodegeneration

A Taylor, F Zhang, X Niu, A Heywood, J Stocks, G Feng… - Neuroimage, 2022 - Elsevier
Neuroimaging-based brain-age estimation via machine learning has emerged as an
important new approach for studying brain aging. The difference between one's estimated …

The Choice of Machine Learning Algorithms Impacts the Association between Brain-Predicted Age Difference and Cognitive Function

WH Lee - Mathematics, 2023 - mdpi.com
Machine learning has been increasingly applied to neuroimaging data to compute
personalized estimates of the biological age of an individual's brain (brain age). The …

Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer's Disease and …

I Cumplido-Mayoral, M García-Prat, G Operto, C Falcon… - Elife, 2023 - elifesciences.org
Brain-age can be inferred from structural neuroimaging and compared to chronological age
(brain-age delta) as a marker of biological brain aging. Accelerated aging has been found in …

Benchmarking the generalizability of brain age models: Challenges posed by scanner variance and prediction bias

RJ Jirsaraie, T Kaufmann, V Bashyam… - Human Brain …, 2023 - Wiley Online Library
Abstract Machine learning has been increasingly applied to neuroimaging data to predict
age, deriving a personalized biomarker with potential clinical applications. The scientific and …

Brain structure ages—A new biomarker for multi‐disease classification

HD Nguyen, M Clément, B Mansencal… - Human Brain …, 2024 - Wiley Online Library
Age is an important variable to describe the expected brain's anatomy status across the
normal aging trajectory. The deviation from that normative aging trajectory may provide …

Improved prediction of brain age using multimodal neuroimaging data

X Niu, F Zhang, J Kounios, H Liang - Human brain mapping, 2020 - Wiley Online Library
Brain age prediction based on imaging data and machine learning (ML) methods has great
potential to provide insights into the development of cognition and mental disorders. Though …