Background Renal fibrosis is a chronic and progressive process affecting kidneys in chronic
kidney disease (CKD). Mesenchymal stem cells-derived exosomes (MSCs-Exo) have been …

Evidence has shown that mesenchymal stem cells'(MSCs) therapy has potential application
in treating chronic kidney disease (CKD). In addition, MSCs-derived exosomes can improve …

Exosomes derived from mesenchymal stem cell (MSC) alleviate kidney damage through
autophagy. This study determined whether MSCs relieve renal fibrosis and inhibit …

Chronic kidney disease (CKD) in clinical is defined as a gradual loss of kidney function for
more than 3 months. The pathologic course of CKD is characterized by extensive renal …

The advancement of microRNA (miRNA) therapies has been hampered by difficulties in
delivering miRNA to the injured kidney in a robust and sustainable manner. Using …

Renal fibrosis (RF) predisposes patients to an increased risk of progressive chronic kidney
disease, and effective treatments remain elusive. Mesenchymal stem cell (MSC)-derived …

Renal fibrosis is a common pathological feature and outcome of almost all chronic kidney
diseases, and it is characterized by metabolic reprogramming toward aerobic glycolysis …

Methods and Results To explore a better treatment, we collected exosomes from pluripotent
stem cell (PSC)-derived mesenchymal stem cells (MSC) and verified their therapeutic effect …

Background Mesenchymal stem cell (MSC)-derived exosomes have seen great advances in
human disease control in a minimally invasive manner. This research aimed to explore the …

Rationale: Ureteral obstruction-induced hydronephrosis is associated with renal fibrosis and
progressive chronic kidney disease (CKD). Exosome-mediated cell-cell communication has …