Understanding how the structural connectivity and spatial geometry of a network constrains the dynamics it is able to support is an active and open area of research. We simulated the …
One of the biggest challenges in biology is to understand how activity at the cellular level of neurons, as a result of their mutual interactions, leads to the observed behavior of an …
Capturing how the Caenorhabditis elegans connectome structure gives rise to its neuron functionality remains unclear. It is through fiber symmetries found in its neuronal connectivity …
The neural dynamics of the nematode C. elegans are experimentally low-dimensional and correspond to discrete behavioral states, where previous modeling work has found neural …
The neural dynamics of the nematode Caenorhabditis elegans are experimentally low- dimensional and may be understood as long-timescale transitions between multiple low …
The work presented in this dissertation grew out of a study of a physiologically based computational model of the tap withdrawal response in the nematode Caenorhabditis …
N Cohen, JE Denham - Current Opinion in Systems Biology, 2019 - Elsevier
With a reconstructed and extensively characterized neural circuit, Caenorhabditis elegans is a fascinating model system for the study of neural circuits and behavior. Here, we review the …
We review mathematical aspects of biophysical dynamics, signal transduction and network architecture that have been used to uncover functionally significant relations between the …
The neural connectome of the nematode Caenorhabditis elegans has been completely mapped, yet in spite of being one of the smallest connectomes (302 neurons), the design …