Synopsis Lisinopril is an orally active angiotensin-converting enzyme (ACE) inhibitor which at dosages of 20 to 80mg once daily is effective in lowering blood pressure in all grades of …
MS Laher, D Natin, SK Rao, RW Jones… - Journal of …, 1987 - journals.lww.com
The antihypertensive efficacy and safety of lisinopril, a long-acting angiotensin-converting enzyme inhibitor, were assessed in 40 elderly patients (aged 65 years or over) with mild to …
SL Chase, JD Sutton - Pharmacotherapy: The Journal of …, 1989 - Wiley Online Library
Lisinopril is a synthetic, nonsulfhydryl, angiotensin‐converting enzyme inhibitor. Its bioavailability is approximately 25% and is not affected by food. Hepatic metabolism is not …
HJ Gomez, SG Smith III, F Moncloa - The American Journal of Medicine, 1988 - Elsevier
Angiotensin-converting enzyme inhibitor therapy has been thought to be more effective in hypertensive patients with normal or elevated levels of renin in the plasma. However …
Lisinopril is a new, nonsulfhydryl angiotensin-converting enzyme inhibitor approved for the treatment of hypertension. After oral administration, 25–29 percent of the dose is absorbed …
TA Noble, KM Murray - Clinical pharmacy, 1988 - europepmc.org
The chemistry, pharmacology, pharmacokinetics, clinical use, adverse effects, and dosage of lisinopril are reviewed. Lisinopril, a new nonsulfhydryl angiotensin-converting-enzyme …
JE Rush, PA Lyle - The American Journal of Medicine, 1988 - Elsevier
The safety and tolerability of lisinopril have been assessed in 1,734 hypertensive patients treated with the agent in a number of clinical trials. Here we compare the clinical and …
AA Ajayi, N Hockings, JL Reid - British journal of clinical …, 1986 - Wiley Online Library
The effect of age on the pharmacodynamic responses to converting enzyme inhibitors, enalapril and enalaprilat was investigated in nine young (22‐30 years) and nine sex …
BAM Van Schaik, GG Geyskes, P Boer - European journal of clinical …, 1987 - Springer
Summary Lisinopril (MK521), a lysine analogue of enalaprilic acid, the bioactive metabolite of enalapril, has a longer half-life than enalaprilic acid, and is excreted unchanged in the …