Safety and potency of BIV1‐CovIran inactivated vaccine candidate for SARS‐CoV‐2: A preclinical study

A Abdoli, R Aalizadeh, H Aminianfar… - Reviews in medical …, 2022 - Wiley Online Library
The development of effective and safe COVID‐19 vaccines is a major move forward in our
global effort to control the SARS‐CoV‐2 pandemic. The aims of this study were (1) to …

Efficacy and safety of an inactivated virus-particle vaccine for SARS-CoV-2, BIV1-CovIran: randomised, placebo controlled, double blind, multicentre, phase 3 clinical …

M Mohraz, K Vahdat, SH Ghamari, M Abbasi-Kangevari… - bmj, 2023 - bmj.com
Objective To report the efficacy, safety, and exploratory immunogenicity findings of two 5 µg
doses of the BIV1-CovIran vaccine. Design Randomised, placebo controlled, double blind …

An overview on inactivated and live‐attenuated SARS‐CoV‐2 vaccines

S Khoshnood, M Arshadi, S Akrami… - Journal of Clinical …, 2022 - Wiley Online Library
After about 2 years since severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2),
first infections were detected in Wuhan city of China in December 2019, which was followed …

Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial

S Xia, Y Zhang, Y Wang, H Wang, Y Yang… - The Lancet infectious …, 2021 - thelancet.com
Background The ongoing COVID-19 pandemic warrants accelerated efforts to test vaccine
candidates. We aimed to assess the safety and immunogenicity of an inactivated severe …

Development of an inactivated vaccine against SARS CoV-2

STI Pavel, H Yetiskin, MA Uygut, AF Aslan, G Aydın… - Vaccines, 2021 - mdpi.com
The rapid spread of SARS-CoV-2 with its mutating strains has posed a global threat to safety
during this COVID-19 pandemic. Thus far, there are 123 candidate vaccines in human …

Safety and immunogenicity of an inactivated virus particle vaccine for SARS-CoV-2, BIV1-CovIran: findings from double-blind, randomised, placebo-controlled, phase I …

M Mohraz, M Salehi, P Tabarsi, M Abbasi-Kangevari… - BMJ open, 2022 - bmjopen.bmj.com
Objective Assessing safety and immunogenicity of an inactivated whole virus particle
vaccine. Design Single-centre, double-blind, randomised, placebo-controlled, phase I (stage …

Immunogenicity and safety of an inactivated SARS-CoV-2 vaccine: preclinical studies

A Kandeil, A Mostafa, RR Hegazy, R El-Shesheny… - Vaccines, 2021 - mdpi.com
Since the emergence of SARS-CoV-2 at the end of 2019, 64 candidate vaccines are in
clinical development and 173 are in the pre-clinical phase. Five types of vaccines are …

Comparison of biological, pharmacological characteristics, indications, contraindications, efficacy, and adverse effects of inactivated whole-virus COVID-19 vaccines …

SA Meo, RA ElToukhy, AS Meo, DC Klonoff - Vaccines, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging viral
zoonotic illness that has developed a distinctive and threatening situation globally …

Immunogenicity and protective efficacy of inactivated SARS-CoV-2 vaccine candidate, BBV152 in rhesus macaques

PD Yadav, R Ella, S Kumar, DR Patil… - Nature …, 2021 - nature.com
The COVID-19 pandemic is a global health crisis that poses a great challenge to the public
health system of affected countries. Safe and effective vaccines are needed to overcome this …

[HTML][HTML] Development of an inactivated vaccine candidate, BBIBP-CorV, with potent protection against SARS-CoV-2

H Wang, Y Zhang, B Huang, W Deng, Y Quan, W Wang… - Cell, 2020 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global public health. The …