A targeted series of chalcone and dienone hybrid compounds containing aminoquinoline
and nucleoside templates was synthesized and evaluated for in vitro antimalarial activity …

We report herein synthesis of a series of 4‐aminoquinoline‐1, 2, 3‐triazole and 4‐
aminoquinoline‐1, 2, 3‐triazole‐1, 3, 5‐triazine hybrids and evaluate their antimalarial …

One of the most viable options to tackle the growing resistance to the antimalarial drugs
such as artemisinin is to resort to synthetic drugs. The multi-target strategy involving the use …

Despite emergence of resistance to CQ and other 4-aminoquinoline drugs in most of the
endemic regions, research findings provide considerable support that there is still significant …

Abstract Triazole tethered 7-chloroquinoline-pyrimidine-5-carboxylate hybrids were
synthesized and evaluated for antiplasmodial activity against chloroquine sensitive (CQ S) …

A series of 4-aminoquinolinyl-chalcone amides 11–19 were synthesized through
condensation of carboxylic acid-functionalized chalcone with aminoquinolines, using 1, 1 …

The parasitic disease malaria places almost half of the world's population at risk of infection
and is responsible for more than 400,000 deaths each year. The first-line treatment …

Click chemistry technique led to novel 1, 2, 3-triazole-quinine conjugates 8a–g, 10a–o, 11a–
h and 13 utilizing benzotriazole-mediated synthetic approach with excellent yields. Some of …

In our efforts to identify novel chemical scaffolds for the development of antimalarial agents,
a series of quinoline− imidazole hybrid compounds were synthesized and their blood-stage …

The present study was carried out in an attempt to synthesize a new class of antimicrobial
and antiplasmodial agents by copper catalyzed click chemistry to afford 25 compounds 10 …