Repeated coronavirus infections in childhood drive progressive maturation of systemic
immune responses into adulthood. Analyses of immune responses in children have focused …

Background: SARS-CoV-2 enters the body through inhalation or self-inoculation to mucosal
surfaces. The kinetics of the ocular and nasal mucosal-specific-immunoglobulin A (IgA) …

Background. Understanding antibody responses to SARS-CoV-2 vaccination is crucial for
refining COVID-19 immunization strategies. Generation of mucosal immune responses …

Background Most studies of immunity to SARS-CoV-2 focus on circulating antibody, giving
limited insights into mucosal defences that prevent viral replication and onward …

SARS-CoV-2 primarily infects cells at mucosal surfaces. Serum neutralizing antibody
responses are variable and generally low in individuals that suffer mild forms of the illness …

Background Mucosal antibodies play a key role in the protection against SARS-CoV-2
infection in the upper respiratory tract, and potentially in limiting virus replication and …

While IgM and IgG response to SARS-CoV-2 has been extensively studied, relatively little is
known about secretory IgA (sIgA) response in respiratory mucosa. Here we report IgA …

Anti-Spike Mucosal IgA Protection against SARS-CoV-2 Omicron Infection | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

SARS-CoV-2 is primarily an airborne infection of the upper respiratory tract, which on
reaching the lungs causes the severe acute respiratory disease, COVID-19. Its first contact …

Although SARS-CoV-2 infects the upper respiratory tract, we know little about the amount,
type, and kinetics of antibodies (Ab) generated in the oral cavity in response to COVID-19 …