[HTML][HTML] von Willebrand factor, endothelial dysfunction, and cardiovascular disease

UM Vischer - Journal of thrombosis and haemostasis, 2006 - Elsevier
Summary von Willebrand factor (VWF), a glycoprotein involved in arterial thrombus
formation, is released into the circulation by secretion from endothelial cells. Plasma VWF …

von Willebrand factor: a marker of endothelial dysfunction in vascular disorders?

GYH Lip, A Blann - Cardiovascular research, 1997 - academic.oup.com
The vascular endothelium is involved in the production of many important substances which
are involved in cardiovascular pathophysiology. One such substance which is synthesised …

[HTML][HTML] Genetic determinants of von Willebrand factor levels and activity in relation to the risk of cardiovascular disease: a review

MPM DE MAAT, FWG LEEBEEK… - Journal of Thrombosis …, 2011 - Elsevier
It is well established that high plasma von Willebrand factor (VWF) levels are associated with
an increased risk of arterial thrombosis, including myocardial infarction and ischemic stroke …

von Willebrand factor and its relevance to cardiovascular disorders.

GY Lip, AD Blann - Heart, 1995 - heart.bmj.com
In the past decade the importance of the vascular endothelium in cardiovascular
pathophysiology has become more apparent. One substance that is synthesised by and …

Plasma von Willebrand factor, thrombosis, and the endothelium: the first 30 years

AD Blann - Thrombosis and haemostasis, 2006 - thieme-connect.com
“It is quite useless to argue the questions concerning the development of intimal scleroses if
we study and discuss the late stages of the disease alone. If we wish to gain insight into the …

Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular disease

MC van Schie, MPM de Maat, A Isaacs… - Blood, The Journal …, 2011 - ashpublications.org
High levels of von Willebrand factor (VWF) are associated with an increased risk for
cardiovascular disease (CVD). Although VWF levels are strongly heritable and genetic …

von Willebrand factor, endothelial cell damage and atherosclerosis

AD Blann, CN McCollum - European journal of vascular surgery, 1994 - Elsevier
von Willebrand factor (vWJ) is an interesting and potentially important molecule whose
biology in health and disease warrants attention. A growing body of knowledge now …

Thrombosis and von Willebrand factor

M Shahidi - Thrombosis and Embolism: from Research to Clinical …, 2017 - Springer
One of the key players in both hemostasis and thrombosis is von Willebrand factor (vWF),
which demonstrates a duality between these two processes. Thrombus is structured by …

[HTML][HTML] Reduced prevalence of arterial thrombosis in von Willebrand disease

YV Sanders, J Eikenboom, EM de Wee… - Journal of Thrombosis …, 2013 - Elsevier
Summary Background High von Willebrand factor (VWF) levels are an established risk factor
for arterial thrombosis, including coronary heart disease and ischemic stroke. It has been …

von Willebrand factor and factor VIII as risk factors for arterial and venous thrombosis

I Martinelli - Seminars in hematology, 2005 - Elsevier
Since the early 1990s attempts have been made to elucidate whether high concentrations of
von Willebrand factor (VWF) and factor VIII (FVIII) in plasma are associated with an …