Pore-forming toxins (PFTs) are virulence factors produced by many pathogenic bacteria and
have long fascinated structural biologists, microbiologists and immunologists. Interestingly …

With the rapid growth of antibiotic-resistant bacteria, it is urgent to develop alternative
therapeutic strategies. Pore-forming toxins (PFTs) belong to the largest family of virulence …

Pore-forming toxins (PFTs) are widely distributed in both Gram-negative and Gram-positive
bacteria. PFTs can act as virulence factors that bacteria utilise in dissemination and host …

Pore-forming toxins (PFTs) are the most common bacterial cytotoxic proteins and are
required for virulence in a large number of important pathogens, including Streptococcus …

Pore-forming toxins (PFTs) are the most common class of bacterial protein toxins and
constitute important bacterial virulence factors. The mode of action of PFT is starting to be …

Pore‐forming toxins (PFTs) are secreted proteins that contribute to the virulence of a great
variety of bacterial pathogens. They inflict one of the more disastrous damages a target cell …

Bacteria, as well as higher organisms such as sea anemones or earthworms, have
developed sophisticated virulence factors such as the pore-forming toxins (PFTs) to mount …

Pore-forming toxins (PFTs) are key virulence determinants produced and secreted by a
variety of human bacterial pathogens. They disrupt the plasma membrane (PM) by …

Pore-forming proteins (PFPs), involved in host–pathogen interactions, are produced as
soluble, generally monomeric, proteins. To convert from the soluble to the transmembrane …

Organisms from all kingdoms produce pore-forming proteins, with the best-characterized
being of bacterial origin. The last decade of research has revealed that the channels formed …