Dry eye disease (DED) is a multifactorial disease of the ocular surface system whose chore
mechanisms are tear film instability, inflammation, tear hyperosmolarity and epithelial …

Purpose To critically appraise scientific evidence regarding the efficacy of nutritional
supplementation with omega‐3 and omega‐6 fatty acids for the treatment of dry eye …

In the homeostasis of the ocular surface, vitamins play a critical role in regulating
inflammatory responses and promoting cell differentiation, development and correct …

Purpose To assess the efficacy of 2 forms of oral long-chain omega-3 (ω-3) essential fatty
acid (EFA) supplements, phospholipid (krill oil) and triacylglyceride (fish oil), for treating dry …

Dry eye disease is a multifactorial pathology compromising the quality of life of patients,
resulting in significant damage of the ocular surface and discomfort. The current …

PURPOSE: Dry eye is a common complaint often encountered in optometric practice.
However, it is a difficult condition to treat as clinical signs do not always correlate with patient …

Purpose Describe trial design and baseline characteristics of participants in the DRy Eye
Assessment and Management (DREAM©) Study. Design Prospective, multi-center …

Purpose: To assess whether omega-3 fatty acid (FA) supplementation is more efficacious
than placebo in amelioration of signs and symptoms of dry eye disease. Methods: We …

To investigate the effects of polyunsaturated fatty acids (PUFAs) in patients with dry eye
disease (DED), a multifactorial inflammatory disorder, we searched Cochrane Library …

Objective To study the efficacy of topical application of alpha-linolenic acid (ALA) and
linoleic acid (LA) for dry eye treatment. Methods Formulations containing ALA, LA, combined …