The rapid emergence and dissemination of antimicrobial-resistant microorganisms in ICUs
worldwide constitute a problem of crisis dimensions. The root causes of this problem are …

The rapid emergence and dissemination of antibiotic-resistant microorganisms in ICUs
worldwide threaten adequate antibiotic coverage of infected patients in this environment …

Antibiotics are one of the most common therapies administered in the intensive care unit
setting. In addition to treating infections, antibiotic use contributes to the emergence of …

The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …

The antibiotic pipeline continues to diminish and the majority of the public remains unaware
of this critical situation. The cause of the decline of antibiotic development is multifactorial …

The prescribing of antibiotics in the ICU is usually empiric, given the critical nature of the
conditions of patients hospitalized there. Appropriate antibiotic utilization in this setting is …

In the face of emerging drug-resistant pathogens and a decrease in the development of new
antimicrobial agents, antibiotic stewardship should be practiced in all critical care units …

Intensive care units (ICUs) are an appropriate focus of antibiotic stewardship program efforts
because a large proportion of any hospital's use of parenteral antibiotics, especially broad …

Patients hospitalized in ICUs are 5 to 10 times more likely to acquire nosocomial infections
than other hospital patients. The frequency of infections at different anatomic sites and the …

Appropriate antimicrobial therapy is essential to ensuring positive patient outcomes.
Inappropriate or suboptimal utilization of antibiotics can lead to increased length of stay …