[HTML][HTML] Zic2 patterns binocular vision by specifying the uncrossed retinal projection

E Herrera, L Brown, J Aruga, RA Rachel, G Dolen… - Cell, 2003 - cell.com
During CNS development, combinatorial expression of transcription factors controls
neuronal subtype identity and subsequent axonal trajectory. Regulatory genes designating …

SoxC transcription factors promote contralateral retinal ganglion cell differentiation and axon guidance in the mouse visual system

T Kuwajima, CA Soares, AA Sitko, V Lefebvre… - Neuron, 2017 - cell.com
Transcription factors control cell identity by regulating diverse developmental steps such as
differentiation and axon guidance. The mammalian binocular visual circuit is comprised of …

Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and-independent mechanisms

C García-Frigola, MI Carreres, C Vegar, C Mason… - 2008 - journals.biologists.com
Axons of retinal ganglion cells (RGCs) make a divergent choice at the optic chiasm to cross
or avoid the midline in order to project to ipsilateral and contralateral targets, thereby …

Zic2 regulates the expression of Sert to modulate eye‐specific refinement at the visual targets

C García‐Frigola, E Herrera - The EMBO journal, 2010 - embopress.org
The development of the nervous system is a time‐ordered and multi‐stepped process that
requires neural specification, axonal navigation and arbor refinement at the target tissues …

Magnitude of binocular vision controlled by islet-2 repression of a genetic program that specifies laterality of retinal axon pathfinding

W Pak, R Hindges, YS Lim, SL Pfaff, DDM O'Leary - Cell, 2004 - cell.com
Pathfinding of retinal ganglion cell (RGC) axons at the midline optic chiasm determines
whether RGCs project to ipsilateral or contralateral brain visual centers, critical for binocular …

Foxd1 is required for proper formation of the optic chiasm

E Herrera, R Marcus, S Li, SE Williams, L Erskine, E Lai… - 2004 - journals.biologists.com
In animals with binocular vision, retinal ganglion cell (RGC) axons from each eye sort in the
developing ventral diencephalon to project to ipsi-or contralateral targets, thereby forming …

Domains of regulatory gene expression and the developing optic chiasm: correspondence with retinal axon paths and candidate signaling cells

RC Marcus, K Shimamura, D Sretavan… - Journal of …, 1999 - Wiley Online Library
In mammals, some axons from each retina cross at the optic chiasm, whereas others do not.
Although several loci have been identified within the chiasmatic region that appear to …

Wiring the binocular visual pathways

V Murcia-Belmonte, L Erskine - International journal of molecular sciences, 2019 - mdpi.com
Retinal ganglion cells (RGCs) extend axons out of the retina to transmit visual information to
the brain. These connections are established during development through the navigation of …

Zic2 regulates retinal ganglion cell axon avoidance of ephrinB2 through inducing expression of the guidance receptor EphB1

R Lee, TJ Petros, CA Mason - Journal of Neuroscience, 2008 - Soc Neuroscience
The navigation of retinal axons to ipsilateral and contralateral targets in the brain depends
on the decision to cross or avoid the midline at the optic chiasm, a critical guidance …

The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse

T Pratt, NMML Tian, TI Simpson, JO Mason, DJ Price - 2004 - journals.biologists.com
During normal development, retinal ganglion cells (RGCs) project axons along the optic
nerve to the optic chiasm on the ventral surface of the hypothalamus. In rodents, most RGC …