METTL14‐mediated lncRNA XIST silencing alleviates GDM progression by facilitating trophoblast cell proliferation and migration via the miR‐497‐5p/FOXO1 axis

Y Li, Y Liu, X Yao, H Wang, Z Shi… - Journal of Biochemical …, 2024 - Wiley Online Library
Gestational diabetes mellitus (GDM), a prevalent complication during the gestation period,
has been linked to impaired proliferation and migration of trophoblasts causing placental …

LncRNA XIST promotes insulin resistance in gestational diabetes mellitus via the microRNA-181b-5p/NDRG2 axis.

Y Xu, X Kang, H Liu, H Jiang… - General Physiology & …, 2023 - search.ebscohost.com
Many studies have explored the role of lncRNA X inactivation-specific transcript (XIST) in
diabetes. This study was designed to unravel the regulatory mechanism of XIST on animal …

[HTML][HTML] LncRNA XIST serves as a diagnostic biomarker in gestational diabetes mellitus and its regulatory effect on trophoblast cell via miR-497-5p/FOXO1 axis

Y Li, X Yuan, Z Shi, H Wang, D Ren… - Cardiovascular …, 2021 - ncbi.nlm.nih.gov
Background Gestational diabetes mellitus (GDM) is increasingly common in pregnancy. This
study's purpose was to identify the expression of XIST and manifest the potential mechanism …

[HTML][HTML] Long non-coding RNA Xist regulates oocyte loss via suppressing miR-23b-3p/miR-29a-3p maturation and upregulating STX17 in perinatal mouse ovaries

M Zhou, X Liu, E Qiukai, Y Shang, X Zhang, S Liu… - Cell death & …, 2021 - nature.com
The fecundity of female mammals is resolved by the limited size of the primordial follicle (PF)
pool formed perinatally. The establishment of PF pool is accompanied by a significant …

lncRNA FOXD2-AS1 affects trophoblast cell proliferation, invasion and migration through targeting miRNA

Y Zhang, X Chen - Zygote, 2020 - cambridge.org
The abnormal expression of lncRNAs and miRNAs has been found in the placentas of
patients with preeclampsia (PE). Therefore, we determined the role of lncRNA FOXD2 …

Study on the regulation of trophoblast activity by abnormally expressed lncRNA CCDC144NL-AS1 in patients with gestational diabetes mellitus

D Cao, Y Wang - Hormone and Metabolic Research, 2023 - thieme-connect.com
Gestational diabetes mellitus (GDM) is a common complication in pregnant women. The
growth and differentiation of trophoblast cells determine the function of the placenta, and …

[HTML][HTML] METTL3-mediated lncRNA HOXD-AS1 stability regulates inflammation, and the migration and invasion of trophoblast cells via the miR-135a/β-TRCP axis

L Wang, L Shi, B Zhou, L Hong, H Gong… - Non-coding RNA Research, 2024 - Elsevier
Background Preeclampsia (PE) is a serious pregnancy-specific syndrome associated with
the inadequate invasion of trophoblast cells and inflammation of the uterus. A previous study …

Lnc-HZ08 regulates BPDE-induced trophoblast cell dysfunctions by promoting PI3K ubiquitin degradation and is associated with miscarriage

J Xie, T Liang, J Zhao, Z Xu, P Tian, R Wang… - Cell biology and …, 2022 - Springer
Increasing evidences have shown that pregnant women might miscarry after exposure with
environmental BaP (benzo (a) pyrene). Additionally, BPDE (benzo (a) pyren-7, 8-dihydrodiol …

[HTML][HTML] miR-142-3p promotes pancreatic β cell survival through targeting FOXO1 in gestational diabetes mellitus

T Zhang, C Ji, R Shi - International journal of clinical and …, 2019 - ncbi.nlm.nih.gov
Gestational diabetes mellitus (GDM) is a common metabolic disease during pregnancy with
serious harm. However, the pathogenesis of GDM has not been thoroughly studied. Recent …

MicroRNA-362-5p promotes the proliferation and inhibits apoptosis of trophoblast cells via targeting glutathione-disulfide reductase

C Zhang, D Zhao - Bioengineered, 2021 - Taylor & Francis
Gestational diabetes mellitus (GDM), a common complication of pregnancy, harms the
health of pregnant women and fetuses. MicroRNAs (miRNAs) dysregulation in placenta is …