[HTML][HTML] Voxel-wise multivariate analysis of brain-psychosocial associations in adolescents reveals six latent dimensions of cognition and psychopathology

RA Adams, C Zor, A Mihalik, K Tsirlis, M Brudfors… - Biological Psychiatry …, 2024 - Elsevier
Background Adolescence heralds the onset of much psychopathology, which may be
conceptualized as an emergence of altered covariation between symptoms and brain …

Mapping common grey matter volume deviation across child and adolescent psychiatric disorders

T Li, L Wang, JA Camilleri, X Chen, S Li… - … & biobehavioral reviews, 2020 - Elsevier
Childhood and adolescence represent a time notable for the emergence of many psychiatric
disorders, where comorbidity and co-occurrence of symptoms are well-documented …

Limited generalizability of multivariate brain-based dimensions of child psychiatric symptoms

B Xu, L Dall'Aglio, J Flournoy, G Bortsova… - Communications …, 2024 - nature.com
Multivariate machine learning techniques are a promising set of tools for identifying complex
brain-behavior associations. However, failure to replicate results from these methods across …

A shared multivariate brain-behavior relationship in a Transdiagnostic sample of adolescents

J Bashford-Largo, H Nakua, RJR Blair… - Biological Psychiatry …, 2024 - Elsevier
Background Internalizing and externalizing psychopathology typically present in early
childhood and can have negative implications on general functioning and quality of life …

Tracking brain development and dimensional psychiatric symptoms in children: a longitudinal population-based neuroimaging study

RL Muetzel, LME Blanken… - American Journal of …, 2018 - Am Psychiatric Assoc
Objective: Psychiatric symptomatology during childhood predicts persistent mental illness
later in life. While neuroimaging methodologies are routinely applied cross-sectionally to the …

Linked patterns of biological and environmental covariation with brain structure in adolescence: a population-based longitudinal study

A Modabbernia, A Reichenberg, A Ing, DA Moser… - Molecular …, 2021 - nature.com
Adolescence is a period of major brain reorganization shaped by biologically timed and by
environmental factors. We sought to discover linked patterns of covariation between brain …

Genetic and phenotypic associations between brain imaging, psychopathology and educational attainment in children aged 9-11

S Fernandez-Cabello, D Alnæs, D van der Meer… - medRxiv, 2022 - medrxiv.org
Background Psychiatric disorders are highly heritable and polygenic, and many have their
peak onset in late childhood and adolescence, a period of tremendous changes. Although …

Brain morphometry points to emerging patterns of psychosis, depression, and anxiety vulnerability over a 2-year period in childhood

TG Vargas, VA Mittal - Psychological Medicine, 2023 - cambridge.org
Background Gray matter morphometry studies have lent seminal insights into the etiology of
mental illness. Existing research has primarily focused on adults and then, typically on a …

Multimodal neural correlates of childhood psychopathology

V Kebets, C Piguet, J Chen, LQR Ooi, M Kirschner… - bioRxiv, 2023 - biorxiv.org
Complex structural and functional changes occurring in typical and atypical development
necessitate multidimensional approaches to better understand the risk of developing …

[HTML][HTML] Associations between brain imaging and polygenic scores of mental health and educational attainment in children aged 9–11

S Fernandez-Cabello, D Alnæs, D van der Meer… - Neuroimage, 2022 - Elsevier
Psychiatric disorders are highly heritable and polygenic, and many have their peak onset in
late childhood and adolescence, a period of tremendous changes. Although the …