K18-and CAG-hACE2 transgenic mouse models and SARS-CoV-2: implications for neurodegeneration research
S Dedoni, V Avdoshina, C Camoglio, C Siddi, W Fratta… - Molecules, 2022 - mdpi.com
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a
global pandemic that might lead to very serious consequences. Notably, mental status …
global pandemic that might lead to very serious consequences. Notably, mental status …
The spatial and cell-type distribution of SARS-CoV-2 receptor ACE2 in the human and mouse brains
By engaging angiotensin-converting enzyme 2 (ACE2 or Ace2), the novel pathogenic
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades host cells and …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades host cells and …
SARS-CoV-2 infects primary neurons from human ACE2 expressing mice and upregulates genes involved in the inflammatory and necroptotic pathways
Transgenic mice expressing human angiotensin-converting enzyme 2 under the cytokeratin
18 promoter (K18-hACE2) have been extensively used to investigate the pathogenesis and …
18 promoter (K18-hACE2) have been extensively used to investigate the pathogenesis and …
SARS-CoV-2 infectivity and neurological targets in the brain
WJ Lukiw, A Pogue, JM Hill - Cellular and molecular neurobiology, 2022 - Springer
The gateway for invasion by the novel severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) into human host cells is via the angiotensin-converting enzyme 2 (ACE2) …
(SARS-CoV-2) into human host cells is via the angiotensin-converting enzyme 2 (ACE2) …
A peek into Pandora's box: COVID-19 and neurodegeneration
A Chandra, A Johri - Brain Sciences, 2022 - mdpi.com
Ever since it was first reported in Wuhan, China, the coronavirus-induced disease of 2019
(COVID-19) has become an enigma of sorts with ever expanding reports of direct and …
(COVID-19) has become an enigma of sorts with ever expanding reports of direct and …
Ubiquity of the SARS-CoV-2 receptor ACE2 and upregulation in limbic regions of Alzheimer's disease brain
Y Zhao, W Li, W Lukiw - Folia neuropathologica, 2021 - termedia.pl
The major route of entry for the severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) into human host cells is by means of the angiotensin-converting enzyme-2 (ACE2) …
CoV-2) into human host cells is by means of the angiotensin-converting enzyme-2 (ACE2) …
[HTML][HTML] Towards neuro-covid-19
F Chiappelli - Bioinformation, 2020 - ncbi.nlm.nih.gov
CoViD-19 is the current pandemic caused by the Severe Acute Respiratory Syndrome
Corona Virus-2 (SARS-CoV-2). Infection by SARS-CoV-2 occurs via the binding of its S …
Corona Virus-2 (SARS-CoV-2). Infection by SARS-CoV-2 occurs via the binding of its S …
Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host–virus interaction, and proposed neurotropic mechanisms
The recent outbreak of coronavirus infectious disease 2019 (COVID-19) has gripped the
world with apprehension and has evoked a scare of epic proportion regarding its potential to …
world with apprehension and has evoked a scare of epic proportion regarding its potential to …
Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-human ACE2 transgenic mice
GM Olivarria, Y Cheng, S Furman, C Pachow… - Journal of …, 2022 - Am Soc Microbiol
ABSTRACT Unlike SARS-CoV-1 and MERS-CoV, infection with SARS-CoV-2, the viral
pathogen responsible for COVID-19, is often associated with neurologic symptoms that …
pathogen responsible for COVID-19, is often associated with neurologic symptoms that …
Does COVID19 infect the brain? If so, smokers might be at a higher risk
COVID19 is a devastating global pandemic with epicenters in China, Italy, Spain, and now
the United States. While the majority of infected cases appear mild, in some cases …
the United States. While the majority of infected cases appear mild, in some cases …