Cortical morphology is a key determinant of cognitive ability and mental health. Its
development is a highly intricate process spanning decades, involving the coordinated …

A wealth of empirical evidence is accumulating on the genetic mediation of brain structure
phenotypes. This comes from twin studies that assess heritability and genetic covariance …

The thickness of the cerebral cortical sheet and its surface area are highly heritable traits
thought to have largely distinct polygenic architectures. Despite large-scale efforts, the …

INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities.
Variations in human cortical surface area and thickness are associated with neurological …

Imaging genetics aims to identify genetic variants associated with the structure and function
of the human brain. Recently, collaborative consortia have been successful in this goal …

Recent work in imaging genetics suggests high levels of genetic overlap within cortical
regions for cortical thickness (CT) and surface area (SA). We model this multivariate system …

Neuroimaging genomics is a relatively new field focused on integrating genomic and
imaging data in order to investigate the mechanisms underlying brain phenotypes and …

Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …

Little is known about how genetic variation contributes to neuroanatomical variability, and
whether particular genomic regions comprising genes or evolutionarily conserved elements …

Human brain anatomy is strikingly diverse and highly inheritable: genetic factors may
explain up to 80% of its variability. Prior studies have tried to detect genetic variants with a …