Mesenchymal stromal cells and CAR‐T cells in regenerative medicine: The homing procedure and their effective parameters

H Kolahi Azar, A Imanpour, H Rezaee… - European journal of …, 2024 - Wiley Online Library
Mesenchymal stromal cells (MSCs) and chimeric antigen receptor (CAR)‐T cells are two
core elements in cell therapy procedures. MSCs have significant immunomodulatory effects …

Harnessing mesenchymal stem cell homing as an anticancer therapy

A Hagenhoff, CJ Bruns, Y Zhao… - Expert opinion on …, 2016 - Taylor & Francis
ABSTRACT Introduction: Mesenchymal stromal cells (MSCs) are non-hematopoietic
progenitor cells that have been exploited as vehicles for cell-based cancer therapy. The …

Mesenchymal stem cell therapy: immunomodulation and homing mechanisms

H Yagi, A Soto-Gutierrez, Y Kitagawa… - Stem Cells and Cancer …, 2012 - Springer
Mesenchymal stem cells (MSC) have been explored as a new clinically relevant cell type to
repair injured tissue. A growing corpus of studies have highlighted two important aspects of …

Improving homing in T cell therapy

D Vignali, M Kallikourdis - Cytokine & Growth Factor Reviews, 2017 - Elsevier
Cytotoxic T lymphocytes (cytotoxic T cells, CTLs) are an immune effector cell population that
can mediate specific immune responses against cancer. Based on this concept, tumor …

Strategies to improve homing of mesenchymal stem cells for greater efficacy in stem cell therapy

H Naderi‐Meshkin, AR Bahrami… - Cell biology …, 2015 - Wiley Online Library
Stem/progenitor cell‐based therapeutic approach in clinical practice has been an elusive
dream in medical sciences, and improvement of stem cell homing is one of major challenges …

[HTML][HTML] Homing and migration of mesenchymal stromal cells: how to improve the efficacy of cell therapy?

A De Becker, I Van Riet - World journal of stem cells, 2016 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …

Organ-specific migration of mesenchymal stromal cells: Who, when, where and why?

AS Cornelissen, MW Maijenburg, MA Nolte… - Immunology …, 2015 - Elsevier
Mesenchymal stromal cells (MSC) represent a type of multipotent cells that can differentiate
to various mesenchymal lineages. MSC can be isolated from different tissues and require ex …

Mesenchymal stromal cell homing: mechanisms and strategies for improvement

M Ullah, DD Liu, AS Thakor - Iscience, 2019 - cell.com
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …

Homing pathways of mesenchymal stromal cells (MSCs) and their role in clinical applications

E Deak, E Seifried, R Henschler - International reviews of …, 2010 - Taylor & Francis
Mesenchymal stromal cells (MSCs) have come into focus for an increasing number of
cellular therapies. Since most clinical protocols use intravenous application of MSCs, it has …

[PDF][PDF] Mesenchymal stem cell biodistribution, migration, and homing in vivo

W Zhao, DG Phinney, D Bonnet, M Dominici… - 2014 - escholarship.org
Mesenchymal stem cells (MSCs) were originally defined by their capacity to differentiate into
various connective tissue lineages as well as support hematopoiesis in vitro via the …